CHAPTER 1 - Protein Structure
1.1 Polypeptide chain
1.2 Ligand binding
1.3 Active site
1.3 Structure-function
CHAPTER 2 - Conformational transitions
2.1 Types of transitions in molecular systems
2.2 Conformational states
2.3 Quantum motions
2.4 Myoglobin and hemoglobin
2.5 Cytochromes
2.6 Tobacco mosaic virus coat protein
2.7 Fibrin-fibrinogen
2.8 Conformational changes of side chains in protein interior as a basis of the conformational states of the molecule
CHAPTER 3 – Allosteric regulation
3.1 Proteins
3.2 Nucleic acids
3.3 Small ligands
CHAPTER 4 – Protein channels
4.1 Structure-function
4.2 Signaling
CHAPTER 5 - Helical assemblies
5.1 Determinants of specific helix recognition
5.2 Types of assemblies
CHAPTER 6 - multiprotein complexes
6.1 Postsynaptic density
6.2 Viruses
6.3 Implications in signaling
CHAPTER 7 - Methods of structure determination
7.1 X-Ray crystallography, NMR and Electron Microscopy
7.2 NMR
7.3 Electron Microscopy
CHAPTER 8 – Protein modeling
8.1 Helix and its interactions
8.2 Ligands
8.3 Dynamics
References
Dictionary