PET and SPECT in Neurology

PET and SPECT in Neurology highlight the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable not only to neurologists and radiologists/nuclear medicine specialists but also to interested general practitioners and geriatricians. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.

BASICS: Nuclear Medicine Imaging Tracers for Neurology.- ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography Procedures.- Tracer-Kinetic Modeling.- Quantification in Brain SPECT.- MRI/PET Brain Imaging.- An Investigation of Statistical Power of [¹⁵O]-H₂O PET Perfusion Imaging.- Molecular Imaging Using Magnetic Resonance Spectroscopy in Neurology.- The Default Network of the Brain.- DEMENTIA: Dementia Due to Neurodegenerative Disease – Molecular Imaging Findings.- Abeta Imaging in Aging, Alzheimer’s Disease and Other Neurodegenerative Conditions.- PET Imaging of the Alpha4Beta2*-Nicotinic Acetylcholine Receptors in Alzheimer’s.- Neuroimaging Findings in Mild Cognitive Impairment.- Impact of the IWG/Dubois Criteria for Alzheimer’s Disease in Imaging Studies.- Perfusion SPECT.- Nuclear Imaging in Frontotemporal.- Parkinson Dementia: PET Findings.- SPECT/PET Findings in Lewy Body Dementia.- Vascular.- Value of MIBG in the Differential Diagnosis of Neurodegenerative Disorders.- Linking Molecular Biology to Therapeutic Approaches for Alzheimer Disease with PET.- CEREBROVASCULAR DISORDERS: PET and SPECT Studies of Ageing and Cardiovascular Risk Factors for Alzheimer’s Disease.- Carotid Plaque Imaging with SPECT-CT and PET-CT.- ET in Brain Arteriovenous Malformations and Cerebral Proliferative Angiopathy.- Transient Ischemic Attack.- PET Reveals Pathophysiology in Ischemic Stroke.- MOVEMENT DISORDERS: Parkinson Disease.- SPECT Imaging for Idiopathic M.Parkinson and Parkinsonian Syndromes.- PET and SPECT Imaging in Parkinsonian Syndromes.- Amyotrophic Lateral Sclerosis.- PET in Huntington’s Disease.- PET and SPECT Imaging in Dystonia.- PET and SPECT Imaging in Hyperkinetic Movement Disorders.- Clinical Applications of [¹²³I]FP-CIT SPECT Imaging.- INFLAMMATORY DISORDERS: PET Imaging of Microglia Activation in Neuropsychiatric Disorders with Potential Infectious Origin.- PET Imaging in Multiple Sclerosis.- PET and SPECT Imaging of Neurotoxicity.- PET and SPECT in Hepatic and Uremic Encephalopathy.- EPILEPSY: PET in Epilepsy.- Subtraction ictal SPECT coregistered to MRI (SISCOM).- Nuclear Medicine Neuroimaging and Electromagnetic Source Localization in Nonlesional Drug-Resistant Focal.- TUMORS OF THE NERVOUS SYSTEM: PET Imaging of Gliomas.- Single-Photon Emission Computed Tomography [Neuro-SPECT] Imaging of Brain Tumors.- The Value of ¹¹C-Methionine PET in the Differential Diagnosis between Brain Tumor Recurrence and Radionecrosis.- Imaging Brain Metastases of Neuroendocrine Tumors.- OTHER SUBJECTS: Traumatic Brain Injury.- Whiplash: real or not real? A review and new concept.- Positron Emission Tomography Imaging in Altered States of Consciousness.- Anaesthesia and PET of the Brain.- Modulation of Brain Functioning by Deep Brain Stimulation.- Radionuclide Imaging Studies in Pediatric Neurology.