Pediatric Sleep Medicine - Gozal David (Curatore); Kheirandish-Gozal Leila (Curatore) | Libro Springer 04/2021 -

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gozal david (curatore); kheirandish-gozal leila (curatore) - pediatric sleep medicine

Pediatric Sleep Medicine Mechanisms and Comprehensive Guide to Clinical Evaluation and Management


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Lingua: Inglese


Pubblicazione: 04/2021
Edizione: 1st ed. 2021


This book provides comprehensive coverage of all aspects related to pediatric sleep and its associated disorders. It addresses the ontogeny and maturational aspects of physiological sleep and circadian rhythms, as well as the effects of sleep on the various organ systems as a function of development. 

Organized into nine sections, the book begins with a basic introduction to sleep, and proceeds into an extensive coverage of normative sleep and functional homeostasis. Part three then concisely examines the humoral and developmental aspects of sleep, namely the emerging role of metabolic tissue and the intestinal microbiota in regulation. Parts four, five, and six discuss diagnoses methods, techniques in sleep measurement, and specific aspects of pharmacotherapy and ventilator support for the pediatric patient. Various sleep disorders are explored in part seven, followed by an in-depth analysis of obstructive sleep apnea in part eight. The book concludes with discussions on the presence of sleep issues in other disorders such as Down syndrome, obesity, cystic fibrosis, and asthma. 

Written by recognized leaders in the field, Pediatric Sleep Medicine facilitates an extensive learning experience for practicing physicians who encounter specific sleep-related issues in their practice.


Section (1) Ontogeny, Phylogeny, and Normal Human Sleep

Section (2) Physiologic Regulation in Sleep and During Development

Metabolic  and thermoregulation
Immune function

Section (3) Sleep Mechanisms: Developmental Aspects

Circadian clocks and networks
NREM sleep
REM sleep
Humoral and other sleep promoting factors
Upper airway and motor control during sleep
Sleep homeostasis and sleep regulation
Respiratory control during sleep and wakefulness

Section (4) Measurement of Sleep

Survey tools and screening questionnaires
The pediatric patient with a sleep complaint- initial interview and diagnostic planning
Setting up a pediatric sleep lab
Technologies in the pediatric sleep lab: present and future (actigraphy, CO2, pulse transit time, spectral analysis of EEG, ECG, pulse arterial tonometry, etc…)
Imaging approaches
Laboratory tests in pediatric sleep medicine
The nocturnal polysomnogram – approaches to scoring and interpretation in infants and children
MSLT in children

Section (5) Defining normal in pediatric sleep – reference, normative values

Section (6) Pharmacotherapy Of Sleep Disorders In Children
Wake promoting agents
Somnogenic agents
Drugs which affect sleep

Section (7) Acute And Chronic Ventilatory Support In Children

Supplemental oxygen

Section (8) Disorders of sleep

Insomnia and Insufficient Sleep
Apnea of Infancy, ALTE, and SIDS
Apnea of Prematurity
Obstructive Sleep Apnea
Disorders Of Respiratory Controls And Central Hypoventilation Syndromes
Disorders Of Excessive Sleepiness (Narcolepsy, Idiopathic Hypersomnia)
Circadian Sleep Disorders 

Section (7) Sleep in Other Disorders

Neuromuscular disorders
Cystic fibrosis
Bronchopulmonary dysplasia
Down syndrome
Sickle cell disease
Autism spectrum disorder
Manic depressive disorders
Prader-Willi Syndrome
Craniofacial Syndromes
Developmental delay
Post brain concussion


David Gozal, MD, MBA, PhD 
Department of Child Health
MU Women's and Children’s Hospital
Children’s Hospital Research Institute
University of Missouri
Columbia, MO, USA

Leila Kheirandish-Gozal, MD, MSc
Department of Child Health
Child Health Research Institute
University of Missouri
School of Medicine
Colombia, MO, USA

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Altre Informazioni



Condizione: Nuovo
Dimensioni: 279 x 210 mm Ø 2456 gr
Formato: Copertina rigida
Illustration Notes:64 Illustrations, black and white
Pagine Arabe: 741
Pagine Romane: xx

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