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wass john (curatore); arlt wiebke (curatore); semple robert (curatore) - oxford textbook of endocrinology and diabetes

Oxford Textbook of Endocrinology and Diabetes 3RD EDITION

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Genere:Libro
Lingua: Inglese
Pubblicazione: 03/2022
Edizione: 3° edizione





Note Editore

Now in its third edition, the Oxford Textbook of Endocrinology and Diabetes is an up-to-date, objective and comprehensive text that covers the full scope of endocrinology and diabetes. It contains wide ranging and pragmatic advice on diagnosis and clear guidelines for recommended management, while also covering the scientific principles that underlie the medical practice in this important field. The book has been re-organised into 15 overarching sections, with new sections on Endocrinology of Pregnancy and Management of the Transgender Patient included. All other sections have been extensively updated and restructured. Each chapter is written by an internationally acknowledged expert, relates basic science to evidence based guidelines and clinical management, and where appropriate offers an outline of the controversies in the subject. The textbook has an international focus and deals with subject matter applicable across the globe. The new edition has over 800 images complementing the extensive text and information provided. The book is a 'one-stop' text for trainees and consultants in Endocrinology and Diabetes, residents, those preparing for sub-specialty exams and other professionals allied to the area who need to gain an understanding of the field. It acts as both a point of reference for the experienced consultant as well as a trusted training resource. Purchase of the print work also includes full access to the online edition of the textbook for the life of the edition.




Sommario

1.1 - Endocrine Practice Fundamentals
1.2 - Hormones and receptors: fundamental considerations
1.3 - Molecular aspects of hormonal regulation
1.4 - Endocrinology and evolution: lessons from comparative endocrinology
1.5 - Hormones Across the Lifespan
1.6 - Pituitary assessment strategy
1.7 - Endocrine autoimmunity
1.8 - Common Features of Endocrine Tumours
1.9 - Genetic Aspects of Endocrine Disease
1.10 - Environmental Influences on Endocrine Disease
1.11 - Endocrinology, sleep and circadian rhythms
1.12 - Principles of Hormone replacement
1.13 - Prevention in endocrinology
2.1 - Functional anatomy of the hypothalamus and pituitary
2.2 - The neurohypophysis
2.3 - Aetiology, pathogenesis, and management of disease of the pituitary
2.3.1 - Development of the pituitary and genetic forms of hypopituitarism
2.3.2 - Molecular pathogenesis of pituitary tumours
2.3.3 - Histopathology of pituitary tumours
2.3.4 - Imaging of the pituitary
2.3.5 - Hypopituitarism: replacement of adrenal, thyroid, and gonadal axes
2.3.6 - Adult growth hormone deficiency
2.3.7 - Surgery of pituitary tumours
2.3.8 - Pituitary radiotherapy
2.3.9 - Prolactinomas and hyperprolactinaemia (including macroprolactinaemia)
2.3.10 - Acromegaly
2.3.11 - Clinically nonfunctioning pituitary tumours and gonadotropinomas
2.3.12 - Thyrotropinomas
2.3.13 - Pituitary carcinoma
2.3.14 - Pituitary incidentalomas
2.4 - Aetiology, pathogenesis, and management of diseases of the hypothalamus
2.4.1 - Hypothalamic dysfunction (hypothalamic syndromes)
2.4.2 - Craniopharyngiomas
2.4.3 - Perisellar tumours including cysts, hamartomas, and vascular tumours
2.4.4 - Lymphocytic hypophysitis and other inflammatory conditions of the pituitary
2.5 - Pineal physiology and pathophysiology, including pineal tumours
3.1 - Evaluation of the thyroid patient
3.1.1 - The history and iconography relating to the thyroid gland
3.1.2 - Biosynthesis, transport, metabolism, and actions of thyroid hormones
3.1.3 - Clinical assessment of the thyroid patient
3.1.4 - Thyroid function tests and the effects of drugs
3.1.5 - Nonthyroidal illness syndrome
3.1.6 - Thyroid imaging: nuclear medicine techniques
3.1.7 - Thyroid imaging: nonisotopic techniques
3.1.8 - Epidemiology of thyroid disease and swelling
3.2 - Aetiology of thyroid disorders
3.2.1 - The complex genetics of thyroid disease
3.2.2 - Environmental factors
3.2.3 - Iodine deficiency disorders
3.2.4 - Radiation-induced thyroid disease
3.2.5 - Autoimmune thyroid disease
3.2.6 - Thyroiditis
3.3 - Thyrotoxicosis and related disorders
3.3.1 - Clinical assessment and systemic manifestations of thyrotoxicosis
3.3.2 - Thyrotoxic periodic paralysis
3.3.3 - Thyrotoxic storm
3.3.4 - Subclinical hyperthyroidism
3.3.5 - Causes and laboratory investigations of thyrotoxicosis
3.3.6 - Anti-thyroid drug treatment for thyrotoxicosis
3.3.7 - Radio-iodine treatment of hyperthyroidism
3.3.8 - Surgery for thyrotoxicosis
3.3.9 - Management of Graves hyperthyroidism
3.3.10 - Graves orbitopathy and dermopathy
3.3.11 - Management of toxic multinodular goitre and toxic adenoma
3.3.12 - Management of thyrotoxicosis without hyperthyroidism
3.4 - Hypothyroidism
3.4.1 - Clinical assessment and systemic manifestations of hypothyroidism
3.4.2 - Causes and laboratory investigation of hypothyroidism
3.4.3 - Myxoedema coma
3.4.4 - Subclinical hypothyroidism
3.4.5 - Syndromes of Resistance to Thyroid Hormone
3.4.6 - Treatment of hypothyroidism
3.5 - Thyroid lumps
3.5.1 - Pathogenesis of nontoxic goitre
3.5.2 - Management of nontoxic multinodular goitre
3.5.3 - Management of the single thyroid nodule
3.5.4 - Pathogenesis of thyroid cancer
3.5.5 - Pathology of thyroid cancer
3.5.6 - Papillary, follicular, and anaplastic thyroid carcinoma and lymphoma
3.5.7 - Medullary thyroid carcinoma
4.1 - Parathyroid anatomy, hormone synthesis, secretion, action, and receptors
4.2 - Hypercalcaemia
4.3 - Primary hyperparathyroidism
4.4 - Familial Hypocalciuric Hypercalcemia Types 1-3 and Neonatal Severe Primary Hyperparathyroidism
4.5 - Hypocalcaemic disorders, hypoparathyroidism, and pseudohypoparathyroidism
4.6 - Bones and the KidneyDLThe Practical Conundrum: Distinguishing Between Osteoporosis and the Bone Diseases that Accompany Chronic Renal Failure
4.7 - Hypercalcaemic and hypocalcaemic syndromes in children
4.8 - Osteoporosis
4.9 - Thyroid disorders and bone disease
4.10 - Paget s disease of bone
4.11 - Rickets and osteomalacia (acquired and heritable forms)
4.12 - Glucocorticoid-induced osteoporosis
5.1 - Adrenal imaging
5.2 - Adrenal surgery
5.3 - Adrenal incidentaloma
5.4 - Adrenocortical cancer
5.5.1 - Genetics of phaeochromocytomas, paragangliomas, and neuroblastoma
5.5.2 - Management of phaeochromocytoma and paragagnlioma
5.6.1 - Genetics of primary aldosteronism and other steroid-related causes of endocrine hypertension
5.6.2 - Management of primary aldosteronism
5.7 - Cushing s syndrome
5.8.1 - Genetics of Adrenal Insufficiency
5.8.2 - Management of Adrenal Insufficiency
5.9.1 - Genetics of congenital adrenal hyperplasia
5.9.2 - Modern management of congenital adrenal hyperplasia and prospects for the future
6.1 - Overview and Pathophysiology of Neuroendocrine Neoplasms
6.2 - Neuroendocrine tumour markers
6.3 - Carcinoid syndrome 
6.4.1 - Lung neuroendocrine tumours
6.4.2 - Non-functioning pancreatic neuroendocrine tumours
6.5 - Gastrinoma
6.6 - Insulinoma and hypoglycaemia
6.7 - Glucagonoma
6.8 - Vasointestinal Polypeptide Secreting Tumours
6.9 - Somatostatinoma
6.10 - Imaging neuroendocrine tumours of the gastrointestinal tract/gastroenteropancreatic neuroendocrine tumours (GEP-NET)
6.11 - Multiple endocrine neoplasia type 1
6.12 - Multiple endocrine neoplasia type 2a and 2b
6.13 - Familial syndromes and genetic causes of paraganglioma and phaeochromocytoma  
6.14 - Carney s complex
6.15 - Molecular and Clinical Characteristics Of the McCune-Albright Syndrome
6.16 - Cowden syndrome
7.1 - Growth and its Disorders
7.1.1 - Recognising Normal and Disordered Growth
7.1.2 - Disorders of the GH-IGF Axis
7.1.3 - Short stature in children born small for gestational age
7.1.4 - Growth Disorders with no defined aetiology
7.1.5 - Tall Stature
7.2 - Sex Development
7.2.1 - Sex Determination and Differentiation
7.2.2 - Disorders of Sex Development (DSD) in the newborn
7.2.3 - Recognising Normal and Disordered Pubertal Development
7.2.4 - Pubertal Delay and Hypogonadism
7.2.5 - Precocious Puberty
7.3 - Transition In Endocrinology
8.1 - Normal female endocrinology and ovarian disorders
8.1.1 - Neuroendocrinology of reproduction: the role of hypothalamus and pituitary
8.1.2 - Ovarian and uterine development from fetal life to puberty
8.1.3 - Menstrual cycle and ovulation
8.2 - Evaluation of the female patient with suspected reproductive endocrine disorders
8.2.1 - Clinical evaluation of patient with suspected reproductive endocrine disorders
8.2.2 - Laboratory evaluation
8.3 - Reproductive endocrine disorders
8.3.1 - Disorders of gonadotrophin secreton
8.3.2 - Hyperprolactinaemia
8.3.3 - Premenstrual syndrome
8.4 - Polycystic ovary syndrome and other androgen excess disorders
8.4.1 - Polycystic ovary syndrome: definitions, phenotypes, prevalence and genetics
8.4.2 - Polycystic ovary syndrome: repro




Autore

Professor Wass is a Professor of Endocrinology at Oxford University and was the Head of the Department of Endocrinology at the Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital Oxford, UK until 2011. From 1989 he was Professor of Clinical Endocrinology and Sub-Dean, University of London at Bart's. He founded and ran the Oxfordshire Osteoporosis Service in 1995. John Wass is currently the Clinical Reference Group Chair for Endocrinology in the UK. He was President of the European Federation of Endocrine Societies from 2001-2203 and was Chairman of the Society for Endocrinology (2006-2009). He was awarded the Distinguished Physician of the Year Award by the American Endocrine Society, the first non-American to ever receive this award Elected Academic Vice President of the Royal College of Physicians London in 2012 he has chaired the Royal College of Physicians Working Party 'Action on Obesity: Comprehensive Care for All' published in January 2013. Wiebke Arlt qualified at the University of Cologne in 1990. She trained in Endocrinology from 1994 to 1998 under the auspices of Professor Bruno Allolio at the University Hospital Würzburg, Germany. She then spent two years in the Molecular Endocrinology Lab of the Department of Paediatrics at the University of California in San Francisco (UCSF), hosted by Walter Miller. Following her return to Wuerzburg in 2001 she was appointed Consultant Endocrinologist. She obtained a prestigious Heisenberg Fellowship from the German Research Council and moved to Birmingham in October 2002. In 2004, she obtained an MRC Senior Clinical Fellowship and was appointed Senior Lecturer at the University of Birmingham. Promotion to Chair of Medicine in 2006 and to Head of the Centre for Endocrinology, Diabetes and Metabolism in 2008. She was awarded the William Withering Chair of Medicine in 2014 and appointed as Director of the newly founded Institute of Metabolism and Systems Research in 2015. Professor Semple is an endocrinologist based at the University of Edinburgh, where he is also Dean of Postgraduate Research for the College of Medicine and Veterinary Medicine. His interests include insulin resistance, diabetes, hypoglycaemia and mosaic growth disorders, in each of which he engages in fundamental molecular and cellular research, translational studies, and clinical practice.










Altre Informazioni

ISBN:

9780198870197

Condizione: Nuovo
Dimensioni: 284 x 90.0 x 235 mm Ø 5616 gr
Pagine Arabe: 2656


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