Nutraceuticals and Functional Foods in Human Health and Disease Prevention

Functional foods and nutraceuticals, dietary supplements, and natural antioxidants have established their potential roles in the protection of human health against disease. Nutraceuticals and Functional Foods in Human Health and Disease Prevention examines the benefits, efficacy, and success of properly designed nutraceuticals and functional foods in human health and their possible application in disease prevention. The book demonstrates diverse disease pathophysiology and how nutraceuticals and functional food can be used to combat and prevent disease. The book discusses global food habits and trends, safety and toxicology, and how food addiction or overindulgence of food can lead to a variety of disease states. It then highlights how supplements help in disease prevention. Although a significant number of nutraceuticals and functional foods have demonstrated their efficacy, a large number of supplements are still surviving on false claims. Therefore, the editors underscore risks and benefits, and why government regulatory agencies are so critical of these nutraceutical supplements. With the global nutraceuticals market expected to reach $204.8 billion by 2017, what once seemed a very niche sector has become big business. An overview of nutraceuticals and functional foods and their application in human health, this book exhaustively covers antioxidants, functional foods, and nutraceuticals in human health and disease prevention. With contributions from experts and pioneers, the book gives insight into the role of functional foods in optimal diet and exercise.

INTRODUCTIONGlobal Food Habit and Trend: An OverviewPriyamvadah Kinth and Nimisha KankanSafety and Toxicity of Functional Foods and NutraceuticalsPalma Ann Marone and Kathryn BirkenbachFunctional Foods in the Treatment of Proceßed Food Addiction and the Metabolic SyndromeJ.R. Ifland, Harry G. Preuss, M.T. Marcus, K.M. Rourke, W.C. Taylor, H. Theresa Wright, and K. SheppardNutraceuticals and Their Role in Human Health: A ReviewRunu Chakraborty and Lipi DasOBESITY, DIABETES, AND METABOLIC SYNDROMEDietary Factors in Promoting Healthy Lifestyle: A New Prospect of Neuroendocrine in ObesityRichard Zwe-Ling KongHealth Effects and Weight Loss Benefits of Calorie Restriction Dietary RegimensEric Gumpricht and Krista VaradyOverview of Novel Herbal Supplements in DiabetesNeetu Mishra, Kanti Bhooshan Pandey, and Syed Ibrahim RizviRecommended Diet for Diabetics: Hydrocarbons, Glycemic Impact, Glycemic Load, Glycemic Index, and Mediterranean DietPaulin Moszczyånski and Zbigniew TabarowskiCARDIOVASCULAR HEALTHNutrition and Cardiovascular Health: A ReviewMash Hamid, Clare Stradling, Shahrad Taheri, and G. Neil ThomasARTHRITIS, INFLAMMATION, AND JOINT DISORDERSAntioxidative and Anti-Inflammatory Effects and Health Implications of Berry Polyphenols: Evidence from Compositional and Structural Background to Cell, Animal, and Human StudiesSang Gil Lee, Terrence M. Vance, and Ock K. ChunA Review on the Efficacy of Probiotics in the Treatment of Rheumatic DiseasesElnaz Vaghef-Mehrabany and Leila Vaghef-MehrabanyPhytochemicals as Anti-Inflammatory AgentsKartick C. Pramanik and Atreyi MaitiPOLYUNSATURATED FATTY ACIDS AND SELECTED PHYTOCHEMICALS?-3 PUFA Fatty Acids, Advancing Age, and Brain Function: A ReviewIsabelle Denis and GaËlle Champeil-PotokarStress, Parkinson’s, and Alzheimer’s Disease: Role of Dietary SupplementsRaj K. Keservani, Rajesh K. Kesharwani, Anil K. Sharma, and Mohd Fasih AhmadNutraceuticals and Functional Foods in the Prevention of Mental DisorderRaj K. Keservani, Swati Singh, Virendra Singh, Rajesh K. Kesharwani, and Anil K. SharmaPULMONARY DISEASESPrebiotics, Probiotics, and Synbiotics for the Management of Respiratory DiseaseSeil Sagar, Gert Folkerts, and Johan GarssenPulmonary and Respiratory Health: Antioxidants and NutraceuticalsRaj K. Keservani, Rajesh K. Kesharwani, and Anil K. SharmaHYPERTENSIONNutrition and Nutraceutical Supplements for the Treatment of HypertensionMark HoustonEffects of Different Dietary Fibers on Sugar-Induced Blood Preßure Elevations in Hypertensive Rats: Focus on ViscosityHarry G. Preuß, Debasis Bagchi, Dallas Clouatre, and Nicholas V. PerriconeIMMUNE HEALTHDietary Supplements, Nutraceutical, and Functional Foods in Immune Response (Immunomodulators)Raj K. Keservani, Rajesh K. Kesharwani, Anil K. Sharma, and Urmila JarouliyaCANCERNatural Products in the Prevention of Cancer: A ReviewKelly C. Heim and Michael J. SpinellaHelicobacter pylori Infection and PhytochemicalsArchana ChatterjeeOCULAR HEALTHIntegrative View of the Nutrition of the EyeS.K. Polutchko, J.J. Stewart, and B. Demmig-AdamsPROSTATE HEALTHNutraceuticals for Prostate CancerShigeo HorieSLEEP DISORDERSNutrition and Sleep: An OverviewGlenda Lindseth, Ashley Murray, and Brian HellandWOUND HEALINGOral Supplementation of a Standardized Naturally Fermented Papaya Preparation May Correct Type 2 Diabetes Mellitus-Induced Reactive Oxygen Species DysregulationRyan Dickerson and Sashwati RoyHAIR AND SKIN HEALTHHerbal Treatment for Hair Loss and Alopecia: An OverviewNattaya Lourith and Mayuree KanlayavattanakulNutrition, Nutraceuticals, and Hair GrowthMi-Ryung Kim and Jae-Suk ChoiHerbal Treatment for Skin Wrinkle: An OverviewMayuree Kanlayavattanakul and Nattaya LourithFERTILITY AND SEXUAL HEALTHNutraceuticals and Male Fertility: A ReviewMichelle Lightfoot, Muhannad Alsyouf, and Edmund Y. KoSexual Dysfunctions and Nutraceutical Therapy: An Examination of Human ResearchGene BrunoCOSMECEUTICALSNutraceuticals in CosmeceuticalsPalma Ann MaroneEXERCISE AND PHYSICAL HEALTHNutrition, Functional Foods, and Exercise: A ReviewWataru Aoi and Yuji NaitoSICKLE CELL ANEMIANutraceuticals in the Management of Sickle Cell AnemiaNgozi Awa ImagaROLE OF PROBIOTICS GASTROINTESTINAL AND DENTAL HEALTHHealth Benefits of Human Probiont Lactobacillus plantarumSatish Kumar Ramraj and Arul VenkatesanProbiotic in Functional Gastrointestinal Disorders in Children: Therapy and ReventionFlavia Indrio, Giuseppe Riezzo, and Antonio Di MauroProbiotics and Dental Health: An OverviewMaria Grazia Cagetti, Fabio Cocco, and Guglielmo CampusAntimicrobial Properties of Wild Oregano Extracts: A Compilation and Review of Current ResearchCassim IgramNutraceuticals from MicroalgaeFaruq Ahmed, Faisal Alsenani, and Peer M. Schenk

Debasis Bagchi, PhD, MACN, CNS, MAIChE, received his PhD in medicinal chemistry in 1982. He is a professor in the Department of Pharmacological and Pharmaceutical Sciences at the University of Houston College of Pharmacy, Houston, Texas, and the chief scientific officer of Cepham Research Center, Piscataway, New Jersey. Dr. Bagchi is an adjunct faculty in Texas SouthernUniversity, Houston, Texas. He served as the senior vice president of research and development of InterHealth Nutraceuticals Inc, Benicia, California, from 1998 until February 2011, and then as director of innovation and clinical affairs, of Iovate Health Sciences, Oakville, Ontario, until June 2013. Dr. Bagchi received the Master of American College of Nutrition Award in October 2010. He is the past chairman of International Society of Nutraceuticals and Functional Foods, immediate past president of the American College of Nutrition, Clearwater, Florida, and past chair of the Nutraceuticals and Functional Foods Division of the Institute of Food Technologists, Chicago, Illinois. He is serving as a distinguished advisor on the Japanese Institute for Health Food Standards, Tokyo, Japan. Dr. Bagchi is a member of the Study Section and the Peer Review Committee of the National Institutes of Health, Bethesda, Maryland. Dr. Bagchi has 304 papers in peer-reviewed journals, 26 books, and numerous patents. He has delivered invited lectures in various national and international scientific conferences and organized workshops, and group discussion sessions. Dr. Bagchi is also a member of the Society of Toxicology, member of the New York Academy of Sciences, fellow of the Nutrition Research Academy, and member of the TCE stakeholder Committee of the Wright Patterson Air Force Base, Ohio. He is the associate editor of the Journal of Functional Foods, Journal of the American College of Nutrition, and Archives of Medical and Biomedical Research, and also serves as editorial board member of numerous peer-reviewed journals, including Antioxidants & Redox Signaling, Cancer Letters, Toxicology Mechanisms and Methods, and The Original Internist.Dr. Anand Swaroop earned his MS in biochemistry and PhD in chemistry in 1997. He has gathered over two decades of diversified global management experience in phytopharmaceuticals, global regulations on nutraceuticals and functional foods, chemicals and pharmaceutical ingredients, outsourcing and supply chain management, business development, market research, and strategic planning. He has worked in various multinational pharmaceutical companies including Alembic Ltd. (Vadodara, India), Cadila Laboratories Ltd. (Ahmedabad, India), Nandesari Rasayanee Ltd. (Vadodara, India), Dai-Ichi Laboratories Ltd. (Hyderabad, India), and Yag Mag Labs Pvt. Ltd. (Hyderabad, India) in senior management positions. Currently, he is the founder president of Cepham Inc., Yag Mag Inc., and RALLIFE Inc. (Piscataway, New Jersey) and Cepham Life Sciences Inc. (MD). Dr. Swaroop has several peer-reviewed publications. He is a member of the American Chemical Society (ACS), American Association of Pharmaceutical Scientists (AAPS), American Society of Pharmacognosy (ASP), Council for Responsible Nutrition (CRN), American Botanical Council (ABC), and Natural Products Association (NPA). Dr. Swaroop has organized and chaired numerous sessions in the annual meetings of the Institutes of Food Technologists (IFT) and International Society of Nutraceuticals and Functional Foods (ISNFF) and other scientific meetings. He has also delivered invited lectures in various national and international scientific conferences, organized workshops, and group discussion sessions. Harry G. Preuss, MD, MACN, CNS, received his BA and MD from Cornell University, Ithaca, New York, and New York City, New York; trained for three years in internal medicine at Vanderbilt University Medical Center under Dr. David E. Rogers; studied for two years as a fellow in renal physiology at Cornell University Medical Center under Dr. Robert F. Pitts; and spent two years in clinical and research training in nephrology at Georgetown University Medical Center under Dr. George E. Schreiner. During his training years, he was a special research fellow of the National Institutes of Health (NIH). Following the five years as an assistant and associate (tenured) professor of medicine at the University of Pittsburgh Medical Center where he became an established investigator of the American Heart Association, he returned to Georgetown Medical Center. He subsequently performed a six-month sabbatical in molecular biology at the NIH in the laboratories of Dr. Maurice Burg. Dr. Preuss is now a tenured professor in four departments at Georgetown University Medical Center—biochemistry, physiology, medicine, and pathology.His bibliography includes more than 240 peer-reviewed, original medical research papers, 200 general medical contributions (chapters, review articles, etc.), 7 patents, and more than 250 ab