This book covers relevant concepts in nuclear cardiology, combining imaging techniques and clinical data to do so. Today, nuclear cardiology is a worldwide discipline connected to the broader field of cardiovascular imaging. The combination of clinical aspects (symptoms, medications, previous cardiac procedures), ancillary exams and nuclear images is key to decision-making in clinical practice. Thus, a book on this topic is essential to provide better outcomes for cardiology patients.
The chapters cover a comprehensive range of topics in current cardiology practice, such as ambulatory patients, patients in emergency settings, patients after complex cardiac procedures, and patients during and after the use of cancer therapies that are potentially toxic for the heart (cardio-oncology). As such, multiple clinical scenarios are also presented: patients with suspected coronary disease, patients with heart failure of unknown origin, patients with acute chest pain in the emergency department, patients with suspected pulmonary embolism, patients with complications of the left ventricular assist device, etc. Furthermore, the book describes nuclear cardiology procedures and techniques, discusses the main clinical indications and scenarios for each procedure, presents new technological advances in the field (machine learning and artificial intelligence tools), and mentions the coronavirus disease 2019 (COVID-19) pandemic.
Given its scope, the book offers a valuable guide and videos for various medical professionals, especially cardiologists and nuclear physicians.
Part I – Basics
Chapter 1 – Nuclear Medicine Radiotracers in Cardiology
Chapter 2 – Cardiac PET Procedure
Chapter 3 – Cardiac SPECT Procedure
Chapter 4 – Quantification of Ischemia and Myocardial Blood Flow
Chapter 5 – Cardiac PET/MRI – MRI Techniques Applied to Cardiac PET
Chapter 6 – Non-nuclear Cardiac Imaging Modalities: Echocardiography, CT, MRI and Invasive Coronary Angiography
Chapter 7: Coronary Physiology – From Tracer Kinetics to Invasive FFR and iFR
Chapter 8: Myocardial Metabolism and Ventricular Function
Part II – Coronary Artery Disease
Chapter 9 – Coronary Blood Flow and Myocardial Ischemia
Chapter 10 – Molecular Imaging in Atherosclerotic Vascular Disease
Chapter 11 – PET and SPECT in Stable Ischemic Coronary Disease
Chapter 10 – PET and SPECT in Acute Coronary Syndromes
Chapter 11 – Nuclear Techniques after Coronary Revascularization
Chapter 12 – Physiologic or Anatomic Assessment of CAD: Patient-centered Approach
Chapter 13 – Microvascular Coronary Disease
Part III – Heart Failure
Chapter 14 – Pathophysiology of Heart Failure
Chapter 15 – PET and SPECT in the Evaluation of Viable Myocardium
Chapter 16 – Bone Tracers for the Diagnosis of Cardiac Amyloidosis
Chapter 17 – Adrenergic Nervous System Imaging in HF Management
Chapter 18 – Tako Tsubo Cardiomyopathy and Nuclear Imaging
Chapter 19 – PET and SPECT in Systemic Inflammatory Diseases – Sarcoidosis
Chapter 20 – PET and SPECT in Myocarditis and Vasculitis of Large Vessels
Chapter 20 – Evaluation of Complications of Circulatory Assist Devices
Part IV – Cardiac Arrhythmias
Chapter 21 – Sudden Cardiac Death: Pathophysiology and Clinical Aspects
Chapter 22 – 123I-MIBG in the Risk Stratification of Sudden Cardiac Death
Chapter 23 – Nuclear Imaging Guiding Cardiac Resynchronization Therapy
Part V – Cardiovascular Infections
Chapter 24 – PET and SPECT in Infective EndocarditisChapter 25 – PET and SPECT in Cardiovascular Implantable Electronic Devices Infections
Part VI – Cardio-oncology
Chapter 26 - The Clinical Basis of Heart Damage by Chemo and Radiotherapy
Chapter 27 - Nuclear Medicine Tools for Cardiac Damage Diagnosis in Oncology
Part VII –Nuclear Cardiology use in Emergency Department
Chapter 28 – Chest Pain Evaluation – Diagnosis and Risk Stratification
Chapter 29 – Diagnosis of Pulmonary Embolism
Chapter 30 – Nuclear Medicine in Tako Tsubo Cardiomyopathy
Part VII - Artificial Intelligence in the Practice of Nuclear Cardiology
Chapter 31 - Deep Learning and Artificial Intelligence in Nuclear Cardiology
Claudio Tinoco Mesquita is a Professor at the Radiology Department and Head of the Nuclear Medicine Section at the Hospital Universitário Antonio Pedro, Rio de Janeiro, Brazil. He is also a Coordinator of the Post-Graduate Program in Cardiovascular Sciences at the Universidade Federal Fluminense, Editor-in-Chief of the International Journal of Cardiovascular Sciences, a Consultant of Nuclear Medicine at Pró-Cardíaco Hospital and Hospital Vitória, a Fellow of the American College of Cardiology, and a member of the Society of Nuclear Medicine, European Association of Nuclear Medicine and American Society of Nuclear Cardiology. A past President of the Brazilian Society of Nuclear Medicine (2015-2016), he completed his medical degree at the Universidade Federal Fluminense (1994), a Master’s degree in Medicine (Cardiology) at the Universidade Federal do Rio de Janeiro (1999), and a PhD in Radiology at the Universidade Federal do Rio de Janeiro (2002).
Maria Fernanda Rezende is Coordinator of the Nuclear Medicine Section at Hospital Vitória, Rio de Janeiro, Brazil. She completed her medical degree at Unifenas, Alfenas (2011) and a Master’s degree in Medicine (Cardiology) at the Universidade Federal Fluminense (2015). She is also a Member of the Brazilian Society of Nuclear Medicine.
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