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igarashi eiki - nanomedicines and nanoproducts

Nanomedicines and Nanoproducts Applications, Disposition, and Toxicology in the Human Body




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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

CRC Press

Pubblicazione: 03/2015
Edizione: 1° edizione





Note Editore

Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body provides a detailed overview of the disposition of nanoproducts within the body, with a special focus on the respiratory and olfactory routes of nanoproduct administration, buccal exposure and the ingestion of nanoproducts, the integumentary system (formed by the skin, hair, nails, and associated glands), the ocular route, the systemic route, and toxicology as it relates to the nanoscale world. Offering an interdisciplinary, big-picture view of the current and future state of nanotechnology, this book: Identifies key points for the entry of nanoproducts, nanomedicines, and other nanoscale structures into the body Reviews the bodily administration and subsequent disposition of nanoproducts via various exposure routes Describes the intravenous route of administration for the therapeutic management of ocular disease Discusses practical nanoproduct and nanomedicine applications, disposition, and toxicology Summarizes various toxicological principles and the testing of nanoproducts Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body addresses the scope of practical nanoparticle applications in academic research as well as industrial investigation, where "practical" is defined as advantageous in all aspects of nanoproduct disposition, efficacy, and toxicology. The book’s goal is to introduce potentially beneficial applications and exciting topics regarding nanoproducts to a variety of professional and general readers.




Sommario

Nanoscale WorldScope of NanoproductsDisposition of Nanoproducts and NanoparticlesPolydispersity of Nanoparticles and Penetration Barriers in the BodyPhysicochemical Properties of NanoparticlesHistory of Nanotechnology and NanomedicineOverview of the Nanoscale WorldReferencesOverview of Nanoproduct DispositionPathways for Nanoproduct Absorption, Distribution, and ExcretionLiberation, Absorption, Distribution, Metabolism, and ExcretionLiberationBioavailabilityVolume of DistributionClearanceReferencesRespiratory and Olfactory RoutesAnatomy and PhysiologyPractical Application of Biodegradable NanomedicinesPractical Application of Nonbiodegradable NanomedicinesInhalation of NanoproductsTransport and Liberation of Inhaled ProductsAbsorption via the AlveoliDistribution and TranslocationDisposition of Nanomedicines from the Nasal Cavity to Systemic TissuesClearance of NanoparticlesNanoscale World according to the Respiratory and Olfactory RoutesReferencesBuccal Route and IngestionAnatomy and PhysiologyFactors Affecting Nanoparticle DispositionPractical Applications of NanoproductsRisks and Benefits of Nanoscale Food Packaging Products and NanofoodsBioavailability of Nanomedicines and NanofoodsCellular Endocytosis of NanoparticlesDisposition of Nanoparticles Following Oral AdministrationNanoscale World via the Buccal Route and IngestionReferencesThe Integumentary System and the Ocular RouteAnatomy and PhysiologyPractical Applications in Skin CarePractical Applications in Ocular Medical CareExposure to Sunlight and Nanoparticle ToxicityFactors Affecting Permeability and Disposition in the Integumentary SystemNanoscale World via the Integumentary System and the Ocular RouteReferencesSystemic RouteAnatomy and PhysiologyPathway from Systemic Exposure to Local DeliveryEndocytosis of NanoparticlesNuclear TransportCell Transition/TranslocationPractical Application of NanomedicinesEngineering of NanomedicinesEngineering of Nanoproducts Targeting DiseaseNanoscale World via the Systemic RouteReferencesToxicology in the Nanoscale WorldCharacteristics of ExposureSpectrum of Undesired EffectsToleranceDose-Response RelationshipsDescriptive Animal Toxicity TestsNanoproduct Compatibility with the Immune SystemReferences




Autore

Eiki Igarashi is CEO of Nanosion Co., Ltd., a nanobioventure company in Tokyo, Japan. He is also a guest investigator at the National Institute of Advanced Industrial Science and Technology, Tokyo, Japan, where he collects and reviews medical information regarding the practical application, toxicology, and pharmacokinetics of nanoproducts and nanomaterials, ranging from metallic nanoparticles and carbon nanotubes to nanomedicines, nanofoods, nanocosmeceuticals, and nanoconsumer products. He holds a doctoral degree from Hiroshima University, Japan, and has worked in various capacities with Marion Merrell Dow Co., Ltd. (the pharmaceutical company of the Dow Chemical Company), Hirakata, Japan; Kyoto University, Japan; and Hoechst Marion Roussel Co., Ltd., Tokyo, Japan.










Altre Informazioni

ISBN:

9781498706629

Condizione: Nuovo
Dimensioni: 9.25 x 6.25 in Ø 1.40 lb
Formato: Copertina rigida
Illustration Notes:46 b/w images, 37 color images and 4 tables
Pagine Arabe: 259


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