Series Preface…
Preface…
Table of Contents…
Contributors …
1. Technologies for Screening of mGlu Receptor Allosteric Modulators
Alice L. Rodriguez and Colleen M. Niswender
2. Positron Emission Tomography (PET) Imaging of Metabotropic Glutamate Receptor Subtype 2 (mGlu2) Based on a Negative Allosteric Modulator Radioligand
Xiaofei Zhang, Zhiwei Xiao, Katsushi Kumata, Tomoteru Yamasaki, Lee Josephson, Ming-Rong Zhang, Lu Wang, and Steven H. Liang
3. PET Imaging of Type 5 Metabotropic Glutamate Receptors
Stephanie G. Scala, Kelly Smart, Sylvia M.L. Cox, Chawki Benkelfat and Marco Leyton
4. Electrophysiological and Calcium Imaging Approaches to Study Metabotropic Glutamate Receptors
Philippe Coulon
5. Role of Metabotropic Glutamate Receptors (mGluRs) in the Regulation of Intracellular Calcium Signaling: Theory, Protocols, and Data Analysis
Vaibhav Dhyani, Sarpras Swain, Rishikesh Kumar Gupta, Abha Saxena, Ranjana Singh, and Lopamudra Giri
6. Optical Approaches for Modulating mGlu Receptor Activity
Lauren E. Hood, Jonna M. Leyrer-Jackson, and M. Foster Olive
7. Classic and Modern Approaches to Investigating Interactions between Dopamine Systems and Metabotropic Glutamate Receptors
Kari A. Johnson
8. Using Western Blotting for the Evaluation of Metabotropic Glutamate Receptors within the Nervous System: Procedures and Technical Considerations
Jonna M. Leyrer-Jackson, Mark D. Namba, Lauren E. Hood, and M. Foster Olive
9. Investigation of mGlu Receptor Cell Surface Trafficking in Acute Brain Slices Using Biotinylation
Marek Schwendt
10. Co-Labeling of Neuronal Cells using DiI Neuronal Filling and Immunohistochemistry to Explore Metabotropic Glutamate Receptor Expression
Jonna M. Leyrer-Jackson, Sade Spencer, and Cassandra D. Gipson
11. Fluorescence Immunohistochemistry Techniques for Labelling Metabotropic Glutamate Receptors in the Central Nervous System
Ryan S. Pevey, Jonna M. Leyrer-Jackson, Erin K. Nagy, and M. Foster Olive
12. Multiplex Arrays for Quantifying Relative Levels of Cytokines in Brain Tissue Lysates: Implications for mGlu Receptor Mediated Alterations
Lauren E. Hood, Jonna M. Leyrer-Jackson, Erin K. Nagy, and M. Foster Olive
13. mGlu Receptor Modulation in Murine Models of Stress and Affective Disorders
James Maksymetz and Max E. Joffe
14. Role of Metabotropic Glutamate Receptors in Alcohol Drinking Behaviors
Fawaz Alasmari, Musaad A. Alshammari, and Youssef Sari