Mechanisms of Injury in Renal Disease and Toxicity

Dr. Goldstein has authored more than 50 publications and co-edited two books. Her latest contribution to the field of nephrology, Mechanisms of Injury in Renal Disease and Toxicity, promotes an understanding of the pathophysiologic mechanisms mediating renal dysfunction in disease. It provides an important perspective in understanding mechanisms of chemically induced renal injury. Over the past decade, understanding of the pathophysiologic and molecular basis of renal disease has grown tremendously. New and evolving concepts on the pathophysiology of glomerulonephritis, chronic glomerular injury, diabetic nephropathy, and acute renal failure are changing the clinical management of these disease states.

Mechanisms of Acute and Chronic Renal Failure: Pathophysiologic Mechanisms of Acute Renal Failure (M.S. Paller). Cellular and Molecular Mechanisms of Ischemic Acute Renal Failure and Repair (J. Bonventre and R. Witzgall). Mechanisms of Chronic Glomerular Injury (J.R. Diamond). Role of Eicosanoids in Renal Disease (C.R. Albrightson). Immunologic Mechanisms in Renal Disease (B.D. Schreiber and G.C. Groggel). Mechanisms of Chemically Induced Nephrotoxicity: An Overview of Drug-Induced Nephropathies (J.P. Fillastre and M. Godin). Mechanisms of Chemically Induced Glomerular Injury (C. Cojocel). Renal Drug-Metabolizing Enzymes in Experimental Animals and Humans (E.A. Lock). Role of Metabolism in Chemically Induced Nephrotoxicity (L.H. Lash). Role of Transport in Chemically Induced Nephrotoxicity (W.O. Berndt). Mitochondrial Mechanisms of Tubular Injury (R.G. Schnellman and R.D. Griner). Reactive Oxygen Metabolites and Iron in Toxic Acute Renal Failure (K.A. Nath, N. Ueda, P.D. Walker, and S.V. Shah).