Materiomics High-Throughput Screening of Biomaterial Properties

This complete, yet concise, guide introduces you to the rapidly developing field of high throughput screening of biomaterials: materiomics. Bringing together the key concepts and methodologies used to determine biomaterial properties, you will understand the adaptation and application of materomics in areas such as rapid prototyping, lithography and combinatorial chemistry. Each chapter is written by internationally renowned experts, and includes tutorial paragraphs on topics such as biomaterial-banking, imaging, assay development, translational aspects, and informatics. Case studies of state-of-the-art experiments provide illustrative examples, whilst lists of key publications allow you to easily read up on the most relevant background material. Whether you are a professional scientist in industry, a student or a researcher, this book is not to be missed if you are interested in the latest developments in biomaterials research.

1. Introducing materiomics Nathalie Groen, Steven W. Cranford, Jan de Boer, Markus J. Buehler and Clemens A. van Blitterswijk; 2. Physico-chemical material properties and analysis techniques relevant in high-throughput biomaterials research Erwin Zant, Mirjam J. Bosman and Dirk W. Grijpma; 3. Materiomics using synthetic materials: metals, cements, covalent polymers and supramolecular systems Björne B. Mollet, Bram A. C. H. Pape, Rosa P. Félix Lanao, Sander C. G. Leeuwenburgh and Patricia Y. W. Dankers; 4. Microfabrication techniques in materiomics Hemant Unadkat, Robert Gauvin, Clemens A. van Blitterswijk, Ali Khademhosseini, Jan de Boer and Roman Truckenmüller; 5. Bioassay development Hugo Fernandes, Roderick Beijersbergen, Lino Ferreira, Koen Dechering, Prabhas Moghe and Katharina Maniura-Weber; 6. High-content imaging Frits Hulshof, Er Liu, Andrea Negro, Samy Gobaa, Matthias Lutolf, Prabhas V. Moghe and Hugo Fernandes; 7. Computational analysis of high-throughput material screens Marc Hulsman, Liesbet Geris, and Marcel J. T. Reinders; 8. Upscaling of high-throughput material platforms in two- and three-dimensions Gustavo A. Higuera, Roman K. Truckenmüller, Rong Zhang, Salvatore Pernagallo, Fabien Guillemot and Lorenzo Moroni; 9. Development of materials for regenerative medicine: from clinical need to clinical application Charlène Danoux, Rahul Tare, James Smith, Mark Bradley, John A. Hunt, Richard O. C. Oreffo and Pamela Habibovic; 10. Non-biomedical applications of materiomics Carson Meredith, Sangil Han, Ismael Gomez, Johannes Leisen and Haskell Beckham; 11. Beyond bed and bench Tahir A. Mahmood and Jan de Boer.

Jan de Boer is a professor of applied cell biology at the University of Twente, The Netherlands, at the MIRA Institute for Biomedical Technology and Technical Medicine, where his team performs innovative research on molecular and cellular engineering of bone tissue. He is chair of the Netherlands Society of Biomaterials and Tissue Engineering, and co-founder of the biotech company Materiomics B.V.
Clemens A. van Blitterswijk is a professor of tissue regeneration at the University of Twente, and chair of the Department of Tissue Regeneration at MIRA. Clemens has published over 300 papers and is co-inventor on over 100 patents. He is one of only two individuals to have received both the Jean Leray Award and the George Winter Award, the two prestigious prizes of the European Society for Biomaterials. He was recently appointed Fellow of the Netherlands Academy of Sciences, is Fellow of the Netherlands Academy of Technology and Innovation and Fellow of Biomaterials Science and Engineering.