Male and Sperm Factors that Maximize IVF Success

Male factor infertility is receiving greater emphasis in IVF programs. This book reviews the scientific evidence for various medical, environmental and lifestyle factors that can affect male fertility, such as chromosome abnormalities, age, anti-sperm antibodies and endocrine disruptors. Part of a four-book series on improving IVF success, this volume subsequently explores a range of treatments and strategies to improve sperm quality, including FSH treatment and antioxidants. It also discusses methods to prevent male infertility from childhood through to adulthood. Concise, practical and evidence-based - and with insights from global experts in the field - this text will enable gynecologists, urologists and andrologists to make evidence-based decisions that can influence the success rate of fertilization in subsequent IVF cycles.

1. Sperm selection for ART success R John Aitken; 2. New horizons in male subfertility and infertility Brett Nixon and Elizabeth G. Bromfield; 3. Chromosome abnormalities and the infertile male Csilla Krausz and Viktoria Rosta; 4. The effect of endocrine disruptors and environmental and lifestyle factors on the sperm epigenome Viviane Santana, Albert Salas-Huetos, Emma R. James and Douglas T. Carrell; 5. Lifestyle factors and sperm quality Ciara Wright; 6. The effect of age on male fertility and the health of offspring Allan Pacey and Sarah Martins da Silva; 7. The assessment and role of anti-sperm antibodies Gary N. Clarke; 8. FSH treatment in male infertility Csilla Krausz, Viktoria Rosta and Alberto Ferlin; 9. Antioxidants to improve sperm quality Elena Martínez Holguín, Enrique Lledó García, Ángel Rebollo Román, Javier González García, José Jara Rascón and Carlos Hernández Fernández; 10. The history of utilization of IVF for male factor subfertility Gabor T Kovacs; 11. The case against intracytoplasmic sperm injection for all David Mortimer and Sharon T. Mortimer; 12. Perinatal outcomes from IVF and ICSI Michael Davies; 13. Artificial insemination with partner's sperm for male subfertility Willem Ombelet; 14. Obstructive azoospermia: is there a place for microsurgical testicular sperm extraction? Ahmad Aboukhshaba, Russell P. Hayden and Peter N. Schlegel. 15. Should varicocele be operated on before IVF? Shannon H.K. Kim and Victoria Nisenblat. 16. Donor insemination – Past, present and future perspective Christopher LR Barratt, Rachel Agnew and Eleanor Heighton; 17. DNA damage in spermatozoa Russell P. Hayden, Ahmad Aboukhshaba and Peter N. Schlegel; 18. Prevention of male infertility from childhood to adulthood Alberto Ferlin

R. John Aitken is Laureate Professor of Biological Sciences and Pro Vice-Chancellor of the Faculty of Health and Medicine, University of Newcastle, New South Wales, Australia. His research program focuses on the cell biology of spermatozoa and the origin of mutations in the germ line. He has published over 600 research articles, given more than 430 invited lectures and filed 12 patents.
David Mortimer is founder and Director of Oozoa Biomedical Inc, a Vancouver-based international consulting company that provides advice on IVF laboratory set-up and good practice worldwide. He has been a full-time consultant since 1999, and is an internationally recognized speaker and author in andrology and assisted reproductive technologies.
Gabor T. Kovacs is Professor of Obstetrics and Gynaecology, Monash University, Victoria, Australia. He is also Director of the Obstetrics and Gynaecology Institute, Epworth Healthcare, Melbourne. He has forty years of experience in the treatment of subfertility including IVF, donor insemination, ovulation induction and reproductive surgery. He has edited fourteen books for Cambridge University Press.