Invasive bladder tumors affect the muscle wall, and have a propensity to metastasize and spread to other areas of the body, and are more likely to be fatal. This book presents state-of-the-art diagnoses and treatments available for bladder cancer that has metastasised into the body. A thorough review of current practice is presented in a full color volume with more than 40 tables and 50 illustrations. The book offers a comprehensive review of the subject, covering epidemiology, screening, diagnostic factors, surgery, chemotherapy and post-operative monitoring. Most chapters are jointly written by a basic researcher and a clinician.
Epidemiology and prevention of bladder cancer.- Early diagnosis and screening.- Non-invasive diagnosis.- Molecular pathology of tumour progression and metastasis.- Staging: Past, present and future.- Magnetic resonance imaging.- Prognostic factors.- Surgical management.- Transurethral resection in patients with muscle-infiltrating bladder cancer.- Nodal involvement.- Pre-operative and definitive radiation therapy.- Neo-adjuvant and adjuvant chemotherapy — true and false.- Oncological rationale for function-sparing surgery.- Combination therapy and function-sparing surgery for muscle-invasive bladder cancer.- Chemotherapy of metastatic transitional cell cancer.- Invasive transitional cell cancer in the elderly.- Quality of life.- Urethra involvement and bladder cancer.- Lower urinary tract reconstruction.- Salvage cystectomy.
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