Infertility and Assisted Reproduction

Assisted reproductive technology (ART) is available to two-thirds of the world's population, and world-class experts, representing research from 18 different countries, have contributed to this groundbreaking textbook, detailing the techniques and philosophies behind medical procedures of infertility and assisted reproduction. This is one of the most rapidly changing and hotly debated fields in medicine. Different countries have different restrictions on the research techniques that can be applied to this field, and, therefore, experts from around the world bring varied and unique authorities to different subjects in reproductive technology. Encompassing the latest research into the physiology of reproduction, infertility evaluation and treatment, and assisted reproduction, it concludes with perspectives on the ethical dilemmas faced by clinicians and professionals. This book will be the definitive resource for those working in the areas of reproductive medicine world wide.

Foreword; Part I. Physiology of Reproduction: 1. Folliculogenesis: from prenatal follicles to corpus luteum regression; 2. Mechanisms of follicular development: the role of gonadotrophins; 3. Human follicle culture in vitro; 4. Endometrial receptivity; 5. Molecular mechanisms of implantation-; Part II. Infertility Evaluation and Treatment: 6. Evaluation of the infertile female; 7. Fertiloscopy; 8. Microlaparoscopy; 9. Pediatric and adolescent gynecological laparoscopy; 10. Laparoscopic tubal anastomosis; 11. Tubal microsurgery versus assisted reproduction; 12. The future of operative laparoscopy for infertility; 13. Operative laparoscopy for uterine septum; 14. Lasers in reproductive surgery and infertility; 15. Ultrasonography of the endometrium for infertility; 16. Ultrasonography of the cervix; 17. Transrectal ultrasonography in male infertility; 18. The basic semen analysis: interpretation and clinical application; 19. Evaluation of sperm damage: beyond the WHO criteria; 20. Male factor infertility – state of ART; 21. Diagnosis and treatment of common ejaculatory disorders in a male infertility practice; 22. Ovulation induction; 23. Clomiphene citrate and alternatives for ovulation induction; 24. Aromatase inhibitors for assisted reproduction; 25. Pharmacodynamics and pharmacokinetics of gonadotrophins; 26. The future of gonadotrophins; 27. Ovarian hyperstimulation syndrome; 28. Reducing the risk of high order multiple pregnancy due to ovulation induction; 29. Hyperprolactinemia; 30. Medical management of PCOS; 31. Surgical management of PCOS; 32. Endometriosis associated infertility; 33. Medical management for endometriosis; 34. Reproductive surgery for endometriosis-associated infertility; 35. Congenital uterine malformations and reproduction; 36. Unexplained infertility; 37. Premature ovarian failure (POF): characteristics, diagnosis, and management; Part III. Assisted Reproduction: 38. Medical strategies to improve ART outcome: current evidence; 39. Surgical preparation of the patient for in-vitro fertilizationy; 40. IVF in medically complicated patients; 41. Polycystic ovary syndrome and IVF; 42. Endometriosis and assisted reproductive technology; 43. Evidence-based medicine comparing HMG/FSH and agonist/antagonist and rec/urinary hcg/LH/GnRH to trigger ovulation; 44. Luteal phase support in assisted reproduction; 45. Thrombophilia; 46. Intrauterine insemination; 47. The prediction and management of poor responders in ART; 48. Oocyte donation; 49. In-vitro maturation of oocytes; 50. Oocyte and embryo freezing; 51. Semen cryopreservation; 52. The management of azoospermia; 53. Spermatid injection: current status; 54. Optimizing embryo transfer; 55. Single embryo transfer; 56. Blastocyte transfer; 57. Clinical significance of embryo multinucleation; 58. Quality control in the IVF laboratory; 59. Nursing in assisted reproduction; 60. Clinical outcomes in ART: can the playing field be made level?; 61. Chinese medicine; 62. Complications of assisted reproductive technology; 63. Ectopic and heterotopic pregnancies from IVF; 64. The impact of oxidative stress on female reproduction and ART: an evidence-based review; 65. PGD for chromosomal anomalie; 66. PGD for monogenic disorders and molecular diseases; 67. Epigenetics and ART; 68. Congenital abnormalities and assisted reproductive technology; Part IV. Ethical Dilemmas in Fertility and Assisted Reproduction: 69. Stem cell research; 70. Fertility preservation in male and female patients; 71. Ethical dilemmas in ART: current issues; 72. Infertility treatment in perimenopausal women: ethical considerations; 73. Religious perspectives of ethical issues in ART; 74. The future of assisted reproduction.

Infertility and Assisted Reproduction presents, in detail, the techniques and philosophies behind medical procedures of infertility and assisted reproduction. This comprehensive textbook, with authors from 18 different countries, encompasses the latest research into the physiology of reproduction, infertility evaluation and treatment, and assisted reproduction, and concludes with perspectives on the ethical dilemmas faced by clinicians and professionals.

Dr Botros Rizk is Professor in the Department of Obstetrics and Gynecology and Director of the Division of Reproductive Endocrinology and Infertility at the University of South Alabama.
Dr Juan A. Garcia-Velasco is an Assistant Professor of Obstetrics and Gynecology at Rey Juan Carlos University School of Medicine, Madrid, Spain, and the Director of the Instituto Valenciano de Infertilidad in Madrid.
Dr Hassan Sallam is Professor in Obstetrics and Gynecology, Vice-Dean and Director of Research in the Faculty of Medicine, and the Director of the Suzanne Mubarak Regional Center for Women's Health and Development at the University of Alexandria, Egypt.
Dr Antonis Makrigiannakis is Professor of Obstetrics and Gynecology at the University of Crete Medical School.