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ajmani pritam singh - immunohematology and blood banking

Immunohematology and Blood banking Principles and Practice




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Genere:Libro
Lingua: Inglese
Editore:

Springer

Pubblicazione: 11/2020
Edizione: 1st ed. 2020





Trama

The book covers the basics of genetics and immunology, technical aspects of blood banking and transfusion.It offers a concise, and practical approach for different blood tests and guidelines on the best ways to take donor history, screen donors, store blood components, ensure safety, and anticipate the potentially adverse effects of blood transfusion, components and its management at the bedside. Different chapters include important topics such as collection, storage and transportation of blood, introduction to blood transfusion, blood group serology, discovery of blood groups, donor selection, interview, and its preparation, and storage, pretransfusion testing, transfusion therapy, clinical considerations, and safety, quality assurance, and data management developed specifically for medical technologists and resident doctors. The book also goes beyond preoperative patient blood management, with detailed accounts of coagulation disorder management and the administration of coagulation products and platelet concentrates. The book also defines the components of a learning health system necessary to enable continued improvement in trauma care in both the civilian and the military sectors. This book offers a succinct and user-friendly resource with key points, boxes, tables & charts and is a quick reference guide for pathology and transfusion medicine residents and doctors in blood centers and hospitals dealing with regulatory aspects, transfusion safety, production and storage and donor care.




Sommario

CHAPTER 1

INTRODUCTION TO BLOOD TRANSFUSION

Blood volume

The compatibility test

Definitions of blood product

Indication of blood grouping

Discovery of human blood groups

Hemagglutination reaction

Blood group systems (international society of blood transfusion (ISBT) 2008

Selection of donor for organ donation

Blood test measures antibodies to HLA

Percent reactive antibody (PRA)  

Types of donor for organ transplant

Change of blood group

Bibliography

CHAPTER 2

 BLOOD GROUP & IMMUNOLOGY

Discovery of Blood group

Immunological reaction

Principles of Immunohematology

The ABO antigens

Mendel's First Law of Inheritance

Autosomal chromosome

Genotypes table

What do co-dominant genes mean?

ABO antibodies

 

Antibody characteristics of IgG & IgM

Immunological reaction in blood banking

Stages of immunological reaction

Factors affecting the antigen-antibody reaction

The basic blood group system ABO

Comparison of ABO and Rh (D) groups

Blood groups with natural & immune antibodies

Subgroups of ABO blood group system

Bombay blood group

Plant agglutinins for ABO blood group

Human Leukocyte antigen (HLA)

Anti-human serum (Coomb’s antisera)

Bovine albumin

Rh Antigen

Classification of Rh antigens

Fisher-Race

Wiener

Rosenfield

Identification of Rh antigens

Translating from Weiner to Fisher-Race

Rh antibodies

Rh Blood group & Rh Incompatibility

Variations of the D phenotype

Partial D

Weak D

Laboratory diagnosis of weak D & partial D

Other blood group systems

 

Blood groups with natural & immune antibodies

Lutheran blood group

Miscellaneous blood groups (Human Leukocyte antigen)

Universal recipient

Universal Donor

Extremely rare blood group

 Bibliography

CHAPTER 3

 DONOR BLOOD COLLECTION

Donor consenting process

Essential issues in consent

Ownership of the donation

Donor rights

Ethical issues of donor screening

Signature of the donor

Donor interview

Essentials criteria for blood donors

Criteria for rejecting donors

Donor pre-transfusion evaluation

Guide lines before taking the blood from donor

Donor session records registration & donor identification

Formula for blood to be drawn                             

Blood Donor questionaries’ form

Consent letter from the donor

Whole blood donation

Blood anticoagulation

Blood flow & completion of donation

Blood volume monitoring

Invention of blood bags

Red cell anticoagulant & preservation

Citrate-phosphate-dextrose-adenine (CPDA-1)

Saline –adenine-glucose- mannitol (SAGM)

Types of blood bags

Anticoagulant used in blood bags

Identification of collected blood

Post donation instructions

Management of syncope fainting or vasovagal attack of donor

Donor care after a blood donation

Blood collection record sheet

Bibliography

CHAPTER 4

BLOOD STORAGE AND TRANSPORTATION

Transportation of blood after collection

Storage and transport conditions

Features of a blood transport container

Characteristics of coolant packs used in transportation of blood

Temperature control of transport container

Blood disposal log

Storage of blood

Blood bank refrigerator(s)

Blood plasma freezer(s)

Platelet agitator(s) with built in incubators

Temperature recording devices & alarms

Handling of Blood components

Cold room for preservation of blood

Organization in storage

Changes in stored blood

CPDA-1

Storage of donor  red cell units considerations

Bibliography

CHAPTER 5

TRANSFUSION OF BLOOD AND BLOOD COMPONENTS

Reasons for blood transfusion

Transfusion trigger

Transfusion target

Blood components   for transfusion

Whole blood

Inappropriate indications for the use of packed red blood cells

Packed red blood cells (pRBC)

Life span of transfused packed red blood cells (pRBC)

 Types of aphaeretic red cell concentrate available for treatment of anemia

Transfusion of packed red blood cells (pRBC) in acute anemia

False high Htc in cases of acute hemorrhage

Transfusion regimen for Thalassaemia major

Transfusion of pRBC in patients undergoing chemotherapy

Transfusion of pRBC in thrombocytopenia

Transfusion of pRBCs in chronic anemia

Transfusion of pRBC in sickle cell disease

Indication for auto transfusion

Transfusion of pRBC in bone marrow transplantation

Transfusion of pRBC in neonates

Leukoreduction Indications

Indications for irradiation of pRBC

Side effect of irradiated pRBC

Washed pRBC

Indications of frozen red cells

Fresh Frozen Plasma (FFP)   

Indications

Different types of plasma

Difference between Fresh Frozen Plasma and Plasma Frozen

Properties of different types of plasma

Storage time for preservation of FFP & cryoprecipitate

Plasma thawing equipment

Humate- P antihaemophilic

Advantages of Prothrombin complex concentrate (PCC) over FFP

Side effect of Humate-P

Composition of Prothrombin complex concentrate

Cryoprecipitate

Desmopressin (DDAVP) Indication

Human Fibrin Glue (HFG)

Platelets

Indication of platelets transfusion

Contraindications

Types of platelets

Compatibility

Platelet swirling phenomenon                                                 

Platelet agitator with built in incubator

Medicine & transfusion options

Bibliography

CHAPTER 6

BLOOD COMPONENT PREPERATION

General principles of component preparation

Laboratory procedures in blood component preparation

Preparation of fresh frozen plasma & packed red cells

Chart showing shelf life of blood components

Additive solutions

Preparation of cryoprecipitate

Reconstitution of cryoprecipitate for transfusion

Cryodepleted plasma ("cryosupernatant")

Preparation of platelet rich plasma (PRP)

Preparation of platelet concentrates

Preparation of pRBC

Bibliography

CHAPTER 7

BLOOD TEST IN IMMUNOHEMATOLOGY & BLOOD BANKING

Preparation of reagent cells for blood grouping

Usage of Coomb’s control cells

Preparation of Coomb’s control cells

Reporting of hemagglutination reaction

Procedure of diluting anti –D

Methods of determination of ABO blood grouping

Forward grouping

Reverse grouping

Preparation of Red cell suspension

Indirect antiglobulin test (Du Testing)

Rh (D) Grouping

Pre -transfusion testing (Compatibility testing)

Collection of blood specimen

Blood sample handling and processing

ABO & Rh grouping se




Autore

Dr. Pritam Singh Ajmani, M.D. Pathology and Microbiology, Professor, Department of Pathology, R.D. Gardi medical college, Ujjain, India










Altre Informazioni

ISBN:

9789811584343

Condizione: Nuovo
Dimensioni: 254 x 178 mm Ø 694 gr
Formato: Copertina rigida
Illustration Notes:XXIII, 208 p. 8 illus., 6 illus. in color.
Pagine Arabe: 208
Pagine Romane: xxiii


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