I. Historical Overview: Setting the Context 1. PTSD from DSM-III to DSM-5: Progress and Challenges, Matthew J. Friedman, Paula P. Schnurr, & Terence M. Keane 2. DSM-5 Criteria for PTSD, Matthew J. Friedman, Michelle J. Bovin, & Frank W. Weathers 3. Historical Roots of the PTSD Construct: How PTSD Became a Diagnosis and Launched the Traumatic Stress Field, Alexander C. McFarlane & Dean G. Kilpatrick II. Scientific Foundations and Theoretical Perspectives 4. Epidemiology of Trauma and PTSD in Adults, Kristina J. Korte, Tammy Jiang, Karestan C. Koenen, Sandro Galea, & Jaimie L. Gradus 5. Epidemiology of Trauma and PTSD in Childhood and Adolescence, William E. Copeland & Ellen W. McGinnis 6. Psychological Models of PTSD, Richard A. Bryant 7. Alterations in Memory and Other Neurocognitive Processes, Chris R. Brewin & Jennifer J. Vasterling 8. Trauma-Induced Dissociation, Anne P. DePrince, Martin J. Dorahy, Ruth Lanius, & Francesca L. Schiavone 9. Examining Neurocircuitry and Neuroplasticity in PTSD, Lynnette A. Averill, Christopher L. Averill, Teddy J. Akiki, & Chadi G. Abdallah 10. Neurochemistry, Neuroendocrinology, and Neuroimmunology of PTSD, Ann M. Rasmusson, Byung K. Kim, Tiffany R. Lago, Kayla Brown, Caitlin Ridgewell, & Arieh Y. Shalev 11. Genetics of PTSD, Daniel Bustamante, Kaitlin Bountress, Christina Sheerin, Karestan C. Koenen, Guia Guffanti, Lulu Yan, Michelle Haloossim, Monica Uddin, Nicole Nugent, & Ananda B. Amstadter 12. What Brain Tissue Can Tell Us: Postmortem Brain Banking and Analysis of PTSD Molecular Pathology, Matthew J. Girgenti, Bertrand R. Huber, Matthew J. Friedman, & Ronald S. Duman 13. Gender Issues in PTSD, Rachel Kimerling, Julie C. Weitlauf, & Amy E. Street 14. A Developmental Perspective on Childhood Traumatic Stress, Adam D. Brown, Emily Becker-Weidman, & Glenn N. Saxe 15. Trauma and PTSD in Older Adults, Joan Cook & Vanessa Simiola III. Clinical Practice: Evidence-Based State of the Art 16. Assessment of PTSD and Its Comorbidities in Adults, Nicholas A. Livingston, Deborah J. Brief, Mark W. Miller, & Terence M. Keane 17. Assessment of PTSD in Children and Adolescents, Ernestine C. Briggs, Kate Nooner, & Lisa M. Amaya‑Jackson 18. Early Intervention Following Trauma, Alvi Azad, Leonard Skipper, Gary H. Wynn, & David M. Benedek 19. Psychosocial Treatments for Adults with PTSD, Tara E. Galovski, Carmen P. McLean, C. Adrian Davis, & Jennifer S. Wachen 20. Psychosocial Treatments for Children and Adolescents with PTSD, Judith A. Cohen & Anthony P. Mannarino 21. Empirically Supported Couple and Family Therapies for PTSD, Candice M. Monson, Alexandra Macdonald, Steffany J. Fredman, Jeremiah A. Schumm, & Casey Taft 22. Group Treatments for PTSD, J. Gayle Beck & Denise Sloan 23. Pharmacotherapy for PTSD, Lori Davis, Patricia Pilkinton, & Garrett Aikens 24. Treating PTSD When Common Comorbid Disorders Are Present, Sonya B. Norman, Elizabeth Straus, Robert C. Lyons, Laura D. Crocker, Peter J. Colvonen, & Jessica C. Tripp 25. Trauma Exposure, PTSD, and Physical Health, Paula P. Schnurr, Jennifer S. Wachen, Bonnie L. Green, & Stacey Kaltman IV. Emerging Territory 26. Culture, Trauma, and Traumatic Stress among Refugees, Asylum Seekers, and Postconflict Populations, Derrick Silove & Louis Klein 27. PTSD and the Law: Forensic Considerations, Dean G. Kilpatrick, Alexander C. McFarlane, & Lucy A. Guarnera 28. Technology-Based Interventions for PTSD, Josef I. Ruzek 29. Treating PTSD Using Telemental Health Technology, Leslie A. Morland, Lisa H. Glassman, Carolyn J. Greene, Julia E. Hoffman, & Craig Rosen 30. Psychoneurobiology of Resilience, Lynnette A. Averill, Christopher L. Averill, Robert H. Pietrzak, Dennis S. Charney, & Steven M. Southwick 31. Public Mental Health Interventions Following Disasters, Joshua C. Morganstein, Holly B. Herberman Mash, Mary C. Vance, Carol S. Fullerton, & Robert J. Ursano 32. Dissemination and Implementation of Best Practices in Prevention and Treatment of PTSD, Shannon Wiltsey Stirman 33. Key Questions and an Agenda for Future Research, Matthew J. Friedman, Paula P. Schnurr, & Terence M. Keane