Questo prodotto usufruisce delle SPEDIZIONI GRATIS
selezionando l'opzione Corriere Veloce in fase di ordine.
Pagabile anche con Carta della cultura giovani e del merito, 18App Bonus Cultura e Carta del Docente
This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosimilars and 3D nanofabrication. While bridging the gap between basic biomedical research, engineering, medicine and law, the handbook provides a thorough understanding of nano’s potential to address (i) medical problems from both the patient and health provider's perspective, and (ii) current applications and their potential in a healthcare setting.
GENERAL INTRODUCTION AND BEGINNINGS
NANOPARTICLES, NANODEVICES, AND IMAGING
Properties of Nanoparticulate Materials
Takuya Tsuzuki, PhD
Solid Drug Nanoparticles: Methods for Production and Pharmacokinetic Benefits
Andrew Owen, PhD, and Steve P. Rannard, DPhil
Design and Development of Approved Nanopharmaceutical Products
Heidi M. Mansour, PhD, RPh, Chun-Woong Park, PhD, and Raj Bawa, MS, PhD
Nanosizing Approaches in Drug Delivery
Sandip Chavhan, PhD, Kailash Petkar, PhD, and Krutika Sawant, PhD
Multilayered Nanoparticles for Personalized Medicine: Translation into Clinical Markets
Dania Movia, PhD, Craig Poland, PhD, Lang Tran, PhD, Yuri Volkov, PhD, and Adriele Prina-Mello, PhD
Nanomaterials for Pharmaceutical Applications
Brigitta Loretz, PhD, Ratnesh Jain, PhD, Prajakta Dandekar, PhD, Carolin Thiele, PhD, Yamada Hiroe, PhD, Babak Mostaghaci, PhD, Lian Qiong, MSc, and Claus-Michael Lehr, PhD
Polysaccharides as Nanomaterials for Therapeutics
Shoshy Mizrahy, MSc, and Dan Peer, PhD
The Story of C60 Buckminsterfullerene
Harold W. Kroto, PhD
Applications of Nanoparticles in Medical Imaging
Jason L. J. Dearling, PhD, and Alan B. Packard, PhD
Nanoimaging for Nanomedicine
Yuri L. Lyubchenko, PhD, DSc, Yuliang Zhang, Alexey V. Krasnoslobodtsev, PhD, and Jean-Christophe Rochet, PhD
Nanoparticles for Multi-Modality Diagnostic Imaging and Drug Delivery
Catherine M. Lockhart, PharmD, and Rodney J. Y. Ho, PhD
Magnetic Nanoparticles for Magnetic Resonance Imaging: A Translational Push toward Theranostics
Ryan A. Ortega, Thomas E. Yankeelov, PhD, and Todd D. Giorgio, PhD
First-in-Human Molecular Targeting and Cancer Imaging Using Ultrasmall Dual-Modality C Dots
Michelle S. Bradbury, MD, PhD, and Ulrich Wiesner, PhD
Atomic Force Microscopy for Nanomedicine
Shivani Sharma, PhD, and James K. Gimzewski, PhD
Atomic Force Microscopy Imaging and Probing of Amyloid Nanoaggregates
Yuri L. Lyubchenko, PhD, DSc, and Luda S. Shlyakhtenko, PhD
Image-Based High-Content Analysis, Stem Cells and Nanomedicines: A Novel Strategy for Drug Discovery
Leonardo J. Solmesky, PhD, Yonatan Adalist, MSc, and Miguel Weil, PhD
Viral Nanoparticles: Tools for Materials Science and Biomedicine
Nicole F. Steinmetz, PhD, and Marianne Manchester, PhD
Bacterial Secretion Systems: Nanomachines for Infection and Genetic Diversity
Agnesa Shala, PhD, Michele Ferraro, MSc, and Gerald F. Audette, PhD
The Vascular Cartographic Scanning Nanodevice
Frank J. Boehm
Advancements in Ophthalmic Glucose Nanosensors for Diabetes Management
Angelika Domschke, PhD
THERAPY AND CLINICAL APPLICATIONS
Towards Nanodiagnostics for Bacterial Infections
Georgette B. Salieb-Beugelaar, PhD, and Patrick R. Hunziker, MD
Copaxone® in the Era of Biosimilars and Nanosimilars
Jill B. Conner, MS, PhD, Raj Bawa, MS, PhD, J. Michael Nicholas, PhD, and Vera Weinstein, PhD
Doxil®: The First FDA-Approved Nanodrug—From an Idea to a Product (January 2015 Update)
Yechezkel Barenholz, PhD
Nanotechnology and the Skin Barrier: Topical and Transdermal Nanocarrier-Based Delivery
Hagar I. Labouta, PhD, and Marc Schneider, PhD
Application of Nanotechnology in Non-Invasive Topical Gene Therapy
Mahmoud Elsabahy, PhD, Maria Jimena Loureiro, MSc, and Marianna Foldvari, PhD, DPharmSci
Nanocarriers in the Therapy of Inflammatory Disease
Alf Lamprecht, PhD
Advanced 3D Nano/Microfabrication Techniques for Tissue and Organ Regeneration
Benjamin Holmes, MSc, Thomas J. Webster, PhD, and Lijie Grace Zhang, PhD
Nanomedicine for Acute Lung Injury/Acute Respiratory Distress Syndrome: A Shifting Paradigm?
Ruxana T. Sadikot, MD, and Israel Rubinstein, MD
Nanoviricides: Targeted Anti-Viral Nanomaterials
Randall W. Barton, PhD, Jayant G. Tatake, PhD, and Anil R. Diwan, PhD
Nanotechnology in Tissue Engineering for Orthopaedics
Lesley M. Hamming, PhD, JD, and Mark G. Hamming, MD
Applications of Nanomaterials in Dentistry
Karolina Jurczyk, DDS, PhD, and Mieczyslaw Jurczyk, PhD, DSc
Biomimetic Applications in Regenerative Medicine: Scaffolds, Transplantation Modules, Tissue Homing Devices, and Stem Cells
David W. Green, PhD, and Besim Ben-Nissan, PhD
Potential Applications of Nanotechnology in the Nutraceutical Sector
Shu Wang, MD, PhD, and Jia Zhang, MS
Designing Nanocarriers for the Effective Treatment of Cardiovascular Diseases
Bhuvaneshwar Vaidya, MPharm, PhD, and Suresh P. Vyas, MPharm, PhD
Carbon Nanotubes as Substrates for Neuronal Growth
Cécilia Ménard-Moyon, PhD
Polymeric Nanoparticles for Cancer Therapeutics
Mohit S. Verma, Joshua E. Rosen, Ameena Meerasa, Serge Yoffe, MEng, and Frank X. Gu, PhD
Nanotechnology for Radiation Oncology
Srinivas Sridhar, PhD, Ross Berbeco, PhD, Robert A. Cormack, PhD, and G. M. Makrigiorgos, PhD
Gold Nanoparticles against Cancer
Joan Comenge, PhD, Francisco Romero, PhD, Aurora Conill, MS, and Víctor F. Puntes, PhD
Solid Lipid Nanoparticles and Nanostructured Lipid Carriers for Cancer Therapy
Melike Üner, PhD
Nanomedicines Targeted to Aberrant Cancer Signaling and Epigenetics
Archana Retnakumari, MTech, Parwathy Chandran, MTech, Ranjith Ramachandran, MSc, Giridharan L. Malarvizhi, MTech, Shantikumar Nair, PhD, and Manzoor Koyakutty, PhD
Biodegradable Nanoparticle-Based Antiretroviral Therapy across the Blood-Brain Barrier
Supriya D. Mahajan, PhD, Yun Yu, PhD, Ravikumar Aalinkeel, PhD, Jessica L. Reynolds, PhD, Bindukumar B. Nair, PhD, Manoj J. Mammen, MD, Tracey A. Ignatowski, PhD, Chong Cheng, PhD, and Stanley A. Schwartz, PhD, MD
HIV-Specific Immunotherapy with Synthetic Pathogen-Like Nanoparticles
Orsolya Lorincz, PhD, and Julianna Lisziewicz, PhD
Biomedical Engineering and Nanoneurosurgery: From the Laboratory to the Operating Room
Mario Ganau, MD, PhD, Roberto I. Foroni, PhD, Andrea Soddu, PhD, and Rossano Ambu, MD
Nanotechnology-Based Systems for Microbicide Development
Rute Nunes, Carole Sousa, Bruno Sarmento, PhD, and José das Neves, PhD
Nanotechnology-Based Solutions to Combat the Emerging Threat of Superbugs: Current Scenario and Future Prospects
Nisha C. K
Raj Bawa, MS, PhD, is president of Bawa Biotech LLC, a biotech/pharma consultancy and patent law firm based in Ashburn, Virginia that he founded in 2002. He is an inventor, entrepreneur, professor and registered patent agent licensed to practice before the US Patent & Trademark Office. Trained as a biochemist and microbiologist, he has been an active researcher for over two decades. He has extensive expertise in the pharmaceutical sciences, biotechnology, nanomedicine, drug delivery, biodefense, FDA regulatory issues, and patent law. Since 1999, he has held various adjunct faculty positions at Rensselaer Polytechnic Institute in Troy, NY, where he is currently an adjunct professor of biological sciences and where he received his doctoral degree in three years (biophysics/biochemistry). Since 2004, he has been an adjunct professor of natural and applied sciences at NVCC in Annandale, VA. He is a scientific advisor to Teva Pharmaceutical Industries, Ltd., Israel. He has served as a principal investigator of National Cancer Institute SBIRs and reviewer for both the National Institutes of Health and the National Science Foundation. In the 1990s, Dr. Bawa held various positions at the US Patent & Trademark Office, including primary examiner for 6 years. He is a life member of Sigma Xi, co-chair of the Nanotech Committee of the American Bar Association and serves on the Global Advisory Council of the World Future Society. He has authored over 100 publications, co-edited four texts and serves on the editorial boards of numerous peer-reviewed journals, including serving as a special associate editor of Nanomedicine (Elsevier) and an editor-in-chief of the Journal of Interdisciplinary Nanomedicine (Wiley). Some of Dr. Bawa’s awards include the Innovations Prize from the Institution of Mechanical Engineers, London, UK (2008), the Key Award from Rensselaer’s Office of Alumni Relations (2005) and the Lifetime Achievement Award from the American Society for Nanomedicine (2014).
Gerald F. Audette, PhD, has been a faculty member at York University in Toronto, Canada, since 2006. Currently, he is an associate professor in the Department of Chemistry and acting director of the Centre for Research on Biomolecular Interactions at York University. He received his doctorate in 2002 from the Department of Biochemistry at the University of Saskatchewan in Saskatoon, Canada. Working with Drs. Louis T. J. Delbaere and J. Wilson Quail (1995–2001), Dr. Audette’s research focused on the elucidation of the protein–carbohydrate interactions that occur during blood-group recognition (in particular during the recognition of O blood type) using high-resolution X-ray crystallography. Dr. Audette conducted his postdoctoral research at the University of Alberta (2001–2006) in Edmonton, Canada. Working with Drs. Bart Hazes and Laura Frost; his research again utilized high-resolution protein crystallography to examine the correlation between protein structure and biological activity of type IV pilins that are assembled into pili used by bacteria for multiple purposes, including cellular adhesion during infection. It was during these studies that Dr. Audette identified the generation of protein nanotubes from engineered pilin monomers. Dr. Audette also studied the process of bacterial conjugation (or lateral gene transfer) using the F-plasmid conjugative system of Escherichia coli. Current research directions include: structure/function studies of proteins involved in bacterial conjugation systems, the structural and functional characterization of several type IV pilins (the monomeric subunit of the pilus), their assembly systems, and adapting these unique protein systems for applications in bionanotechnology. Dr. Audette has previously served as co-editor- in-chief of the Journal of Bionanoscience (2007–2010), and is currently a subject editor of structural chemistry and crystallography for the journal FACETS.
Israel Rubinstein, MD, is professor of medicine at the College of Medicine, University of Illinois at Chicago, USA. He is member of the section of pulmonary, critical care, allergy and sleep medicine in the Department of Medicine, University of Illinois at Chicago. He is an attending physician at the University of Illinois Hospital and Health Sciences System and Jesse Brown VA Medical Center in Chicago. Dr. Rubinstein is also the associate chief of staff for research and development at the Jesse Brown Veterans Administration Medical Center. Prior to his appointment at the University of Illinois at Chicago, he was associate professor of medicine at the University of Nebraska Medical Center in Omaha, Nebraska, USA. Dr. Rubinstein received his medical degree from the Hebrew University-Hadassah School of Medicine in Jerusalem, Israel. He was a medical resident in Israel, fellow in respirology at the University of Toronto and a research f
Il sito utilizza cookie ed altri strumenti di tracciamento che raccolgono informazioni dal dispositivo dell’utente. Oltre ai cookie tecnici ed analitici aggregati, strettamente necessari per il funzionamento di questo sito web, previo consenso dell’utente possono essere installati cookie di profilazione e marketing e cookie dei social media. Cliccando su “Accetto tutti i cookie” saranno attivate tutte le categorie di cookie. Per accettare solo deterninate categorie di cookie, cliccare invece su “Impostazioni cookie”. Chiudendo il banner o continuando a navigare saranno installati solo cookie tecnici. Per maggiori dettagli, consultare la Cookie Policy.