This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today.
Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication.
Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems.
This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology.
PART I Glial-Neuronal Interactions in the Control of Hypothalamic Development
Chapter 1: The role of microglia in the developing hypothalamus - Deborah Kurrasch
PART II Glial-Neuronal Interactions in the Control of the Magnocellular Neuroendocrine System
Chapter 2: Structural dynamics in the hypothalamic-neurohypophysial system
Chapter 3: Functional consequences of morphological plasticity in the adult hypothalamo-neurohypophysial system
Daniel L Voisin, Aude Panatier, Stéphane H Oliet
Chapter 4: Synaptic scaling by astrocytesGrant S.J. Gordon and Jaideep S. Bains
Chapter 5: Glial control of extrasynaptic receptor signaling in hypothalamic neurons
PART III Glial-Neuronal Interactions in the Control of Metabolic Function
Chapter 6: Astrocytes in the brain control of systemic metabolism
O Le Thuc, T. Gruber, Matthias H. Tschoep, and Cristina García-Cáceres
Chapter 7: Astrocyte mediation of metabolic hormone effects on energy homeostasisJulie A. Chowen
Chapter 8: Glia-neuron communication: Not a one-way street
Denise D. Belsham
PART IV: Glial-Neuronal Interactions in the Control of the Stress Response
Chapter 9: Neuronal-glial synaptic circuits in the hypothalamusJuhee Haam, Zhiying Jiang, Jeffrey G. Tasker
PART V Glial-Neuronal Interactions in the Control of Reproductive Function
Chapter 10: Microglia, hormones, and behavior
Jaclyn M. Schwarz, Margaret M. McCarthy
Chapter 11: The role of astrocytes in estrogen positive feedback
PART VI Glial-Neuronal Interactions in the Control of the Blood-Brain Barrier
Chapter 12: Unveiling the importance of tanycytes in the control of the dialogue between the brain and the periphery
Chapter 13: Tanycyte-neuronal interactions: Novel mechanisms for regulation of the thyroid axisRonald Lechan, Csaba Fekete
Julie A. Chowen received her B.S. from Lake Superior State University in 1982 and her Ph.D. in Physiology from the University of Washington in 1990. She joined Dr. Luis Miguel García-Segura’s laboratory at the Cajal Institute for Neuroscience in Madrid for her postdoctoral research. In 1999 she established her laboratory in the Department of Endocrinology at the Hospital Infantil Niño Jesús in Madrid. Her research focuses on the neuroendocrine control of metabolism, early nutritional and hormonal influences on long-term metabolism and the role of astrocytes in mediating metabolic signals.
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