Current Research and Clinical Management of Melanoma

In our environmentally conscious society, reports of an increase in the risk of developing several cancers - including melanoma, lymphoma and lung cancer - have excited great controversy. Of these tumors, melanoma has demonstrated the most spectacular increase, generating a considerable body of research. The justification for this volume is found in the need for an up-to-date review of this research. The book represents a comprehensive review of both current research and clinical management of melanoma, arranged in such a way as to be maximally user-friendly to both the basic scientst and the clinician interested in this fascinating disease.

1. Etiology of Melanoma.- 2. Epidemiology of Melanoma.- 3. Early Detection of Melanoma.- 4. The Role of Microscopic Evaluation in the Management of Cutaneous Melanoma.- 5. The Prevention of Cutaneous Malignant Melanoma: High-Risk Groups, Chemoprevention, Education, and Screening.- 6. The Natural History of Melanoma, Including the Pattern of Metastatic Spread and the Biological Basis for Metastases — Staging of Melanoma.- 7. Intraocular Melanomas.- 8. The Molecular Genetics of Human Malignant Melanoma.- 9. Immunology and Immunotherapy of Melanoma.- 10. Positive and Negative Growth Regulation in Melanoma: Growth Factors, Intracellular Signalling, and the Cell Cycle.- 11. The Role of Surgery in Cutaneous Malignant Melanoma.- 12. Chemotherapy of Malignant Melanoma.- 13. Radiotherapy of Melanoma.