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1. Introduction to Mass Spectrometry for Bimolecular Analysis in a Clinical Laboratory
Y. Victoria Zhang and Uttam Garg
2. System Performance Monitoring in Clinical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Shannon Haymond
3. Tandem Mass Spectrometry for the Analysis of Plasma/Serum Acylcarnitines for the Diagnosis of Certain Organic Acidurias and Fatty Acid Oxidation Disorders
David Scott, C. Clinton Frazee III, Bryce Heese, and Uttam Garg
4. Quantification of Plasma S-Adenosylmethionine and S-Adenosylhomocysteine Using Liquid Chromatography Electrospray Tandem Mass Spectrometry
Erland Arning, Brandi Wasek, and Teodoro Bottiglieri
5. Quantitation of Aldosterone in Serum or Plasma Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
J. Grace Van Der Gugten and Daniel T. Holmes
6. Comprehensive Determination of Amino Acids for Diagnosis of Inborn Errors of Metabolism
Stephen M. Roper, Annette L. Weindel, and Dennis J. Dietzen
7. Quantification of Branched-Chain Amino Acids in Plasma by High-Performance Liquid Chromatography-Tandem Mass Spectrometry (LC- MS/MS)
Hamed Piri-Moghadam, Alan Miller, Debra Pronger, Faye Vicente, Joel Charrow, Shannon Haymond, and David C. Lin
8. Quantitation of Butyrylcarnitine, Isobutyrylcarnitine, and Glutarylcarnitine in Urine Using Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS)
Judith A. Hobert, Stephen A. Brose, and Marzia Pasquali
9. Quantification of Free and Total Carnitine in Serum Using Liquid Chromatography Tandem Mass Spectrometry
Serena Baird, C. Clint Frazee III, and Uttam Garg
10. Sensitive and Robust LC-MS/MS Analysis of Salivary Cortisol in Negative Mode
Wayne B. Anderson, Putuma P. Gqamana, and Y. Victoria Zhang
11. Measurement of Urine Free Cortisol and Cortisone by LC-MS/MS
Julie A. Ray, Erik Kish-Trier, and Lisa M. Johnson
12. Laboratory Diagnosis of Cerebral Creatine Deficiency Syndromes by Determining Creatine and Guanidinoacetate in Plasma and Urine
Ning Liu and Qin Sun
13. Quantitation of Estradiol and Testosterone in Serum Using LC-MS/MS
Ryan C. Schofield, Daniel Kirchoff, and Dean C. Carlow
14. Quantitation of Fatty Acids in Serum/Plasma and Red Blood Cells by Gas Chromatography-Negative Chemical Ionization-Mass Spectrometry
Erik Kish-Trier and Tatiana Yuzyuk
15. Quantitation of ?-Aminobutyric Acid in Cerebrospinal Fluid Using Liquid Chromatography Electrospray Tandem Mass Spectrometry
Erland Arning, Brandi Wasek, and Teodoro Bottiglieri
16. A Simple, Fast, and Reliable LC-MS/MS Method for the Measurement of Homovanillic Acid and Vanillylmandelic Acid in Urine Specimens
Vrajesh Pandya and Elizabeth L. Frank
17. Quantitation of Neuroblastoma Markers Homovanillic Acid (HVA) and Vanillylmandelic Acid (VMA) in Urine by Gas Chromatography-Mass Spectrometry (GC/MS)
Melissa Beals, Bheemraj Ramoo, C. Clinton Frazee III, and Uttam Garg
18. Quantification of 5-Hydroxyindoleacetic Acid in Urine by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry
Heather A. Nelson and Elizabeth L. Frank
19. Quantitation of IgG Subclasses in Serum Using Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
J. Grace Van Der Gugten, Daniel T. Holmes, and Andre Mattman
20. Quantification of Insulin Analogs by Liquid Chromatography-High Resolution Mass Spectrometry
Erica M. Fatica, Nicholas E. Larkey, and Ravinder J. Singh
21. Differentiation of Common IGF-1 Variants Using HRAM-MS COM Determination with Follow-Up MS/MS Verification
Nicholas E. Larkey, Erica M. Fatica, and Ravinder J. Singh
22. Monitoring and Identifying Insulin-Like Growth Factor 1 Variants by Liquid Chromatography-High Resolution Mass Spectrometry in a Clinical Laboratory
Ievgen Motorykin, Allison Li, and Zengru Wu
23. Quantitation of Lactate in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray Tandem Mass Spectrometry
Brandi Wasek and Erland Arning
24. Multiplex Lysosomal Enzyme Activity Assay on Dried Blood Spots Using Tandem Mass Spectrometry
Hsuan-Chieh (Joyce) Liao and Hsiao-Jan Chen
25. Plasma Lysosphingolipid Biomarker Measurement by Liquid Chromatography-Tandem Mass Spectrometry
Brandon B. Stauffer and Chunli Yu
26. Detection of 13C-Mannitol and Other Saccharides Using Tandem Mass Spectrometry for Evaluation of Intestinal Permeability, or Leaky Gut
Nicholas E. Larkey, Erica M. Fatica, and Ravinder J. Singh
27. LC-MS/MS Method for High Throughput Analysis of Methylmalonic Acid in Serum, Plasma, and Urine: Method for Analyzing Isomers without Chromatographic Separation
Mark M. Kushnir, Gordon J. Nelson, Elizabeth L. Frank, and Alan L. Rockwood
28. Quantitation of 5-Methyltetrahydrofolate in Cerebrospinal Fluid Using Liquid Chromatography Electrospray Tandem Mass Spectrometry
Erland Arning, Brandi Wasek, and Teodoro Bottiglieri
29. Screening of Organic Acidurias by Gas Chromatography Mass Spectrometry (GC-MS)
David Scott, C. Clinton Frazee III, and Uttam Garg
30. Identification of Urine Organic Acids for the Detection of Inborn Errors of Metabolism Usin
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