Clinical and Basic Immunodermatology

This updated volume provides a “user-friendly” reference for dermatologists, dermatology residents and students, as well as for health care workers in related fields to better understand immune-mediated skin diseases and their therapies.

The focus is on what is needed by the physician/resident or student for betting understanding the pathophysiology of the disease as well as the mechanisms of action of the therapies. The reader can easily read about groups of related diseases as well as groups of related therapies.

The level of complexity of the book is such that it has practical applications on a daily basis but can also be used by the resident as a teaching tool and as a handy source of review for the boards. In addition, it can be used the practicing dermatologist to study for recertification.

The scope of the book is immunology, immunogenetics, immunopathology and immunopharmacology as they relate to clinical dermatology.

Concepts of Fundamental Importance for Understanding Skin Disease.- Cytokines and Chemokines.- Innate and Adaptive Immunity.- Neuroimmunology.- Stress and Immunity.- Toll-Like Receptors.- Conventional and Unconventional T Cells.- Complement System.- Cutaneous Dendritic Cells in Health and Disease.- Antimicrobial Peptides.- Photoimmunology.- Angiogenesis for the Clinician.- Common Skin Diseases.- Contact Dermatitis: Allergic and Irritant.- Atopic Dermatitis.- Psoriasis.- The Immunology of Acne.- Nonmelanoma Skin Cancer.- Immunobiology and Immune-Based Therapies of Melanoma.- Drug Eruptions.- Cutaneous Vasculitis.- Immunodermatology and Viral Skin Infection.- HIV Disease and AIDS.- Bacterial Infections.- Parasitic Infections.- Fungal Infections.- Cutaneous T-Cell Lymphoma.- Graft-Versus-Host Disease.- Allergic Urticaria.- Immunopharmacology.- Biologic Therapies for Inflammatory Disease.- Topical Immune Response Modifiers: Adjuvants.- Topical Immune Response Modifiers: Antiinflammatories.- Traditional Immune-Modulating Drugs.- Topical Corticosteroids.- Vaccines.- Intravenous Immunoglobulins.- Autoimmunity, Immunodeficiency, and Immune — Associated Dermatoses.- Novel Approach to the Evaluation of Primary Immunodeficiencies.- Iatrogenic Immunodeficiency and Skin Disease.- Granulomatosis.- Vitiligo Vulgaris.- Alopecia Areata.- Cutaneous Lupus Erythematosus.- Fibrotic Skin Diseases.- Pemphigus Family of Diseases.- The Pemphigoid Spectrum.- Epidermolysis Bullosa Acquisita.- Immunoglobulin A Dermatoses.

Anthony Gaspari

Stephen K. Tyring

Daniel Kaplan