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Chimerism A Clinical Guide




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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

Springer

Pubblicazione: 12/2018
Edizione: Softcover reprint of the original 1st ed. 2018





Trama

This text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome.  Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented.  

Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts.





Sommario

Part I: Causes of Chimerism in Humans

Chapter 1: Fertilization and Early Embryonic Errors
Nicole L. Draper, Kristy Crooks

Chapter 2: Pregnancy and Multiple Gestations
Linda Marie Randolph, Ramen H. Chmait

Chapter 3: Transplantation and Transfusion
Joel N. Kniep

Part II: Clinical Identification and Consequences of Chimerism

Chapter 4: Relationship Testing and Forensics 
Kayla Sheets, Robert Wenk

Chapter 5: Prenatal Genetic Testing and Screening
Ignatia B. Van den Veyver

Chapter 6: Blood Typing Discrepancies
Opal L. Reddy, Dawn C. Ward, Andrea M. McGonigle

Chapter 7: Hematopoietic Stem Cell Donor Selection and Graft-Versus-Host Disease
Alexa J. Siddon, Christopher A. Tormey

Chapter 8: Passenger Lymphocyte Syndrome
Nicole L. Draper, Jamie E. Kallan

Chapter 9: Chimerism: A Clinical Guide to Tolerance Induction
Andrea R. Merchak, Anita Chhabra, Joseph Leventhal, Suzanne T. Ildstad

Chapter 10: Autoimmune Disease
Nathalie Lambert 

Chapter 11: Cancer
Valentina Cirello, Laura Fugazzola




Autore

Nicole L. Draper, MD
University of Colorado School of Medicine
Department of Pathology
Aurora, CO 
USA










Altre Informazioni

ISBN:

9783030078812

Condizione: Nuovo
Dimensioni: 235 x 155 mm Ø 454 gr
Formato: Brossura
Illustration Notes:XI, 200 p. 20 illus., 15 illus. in color.
Pagine Arabe: 200
Pagine Romane: xi


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