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Cell Movement in Health and Disease brings the several scientific domains related to the phenomena together, establishing a consistent foundation for researchers in this exciting field.
The content is presented in four main section. The first explores the foundations of Cell Movement, including overviews of cellular structure, signaling, physiology, motion-related proteins, and the interface with the cellular membrane. The second part covers the biological aspects of cellular movement, starting with chemical and mechanical sensing, describing the types of cell movement, mechanics at cell level, cell physiology, collective behavior, and the connections with the extracellular matrix. The following chapters provide an overview of the molecular machinery involved and cell-type specific movement. The third part of the book is dedicated to the translational aspects of cell movement, highlighting the key conditions associated with cell movement dysfunction, like cell invasion in cancer, wound healing, developmental issues, neurological dysfunctions, and immune response. The final part of the book covers key methods and modeling tools for cell movement research, including predictive mathematical models, in vitro and in vivo methods, biophysical and bioinformatics tools.
Cell Movement in Health and Disease is the ideal reference for scientists from different backgrounds converging to expand the understanding of this key cellular process. Cellular and molecular biologists will gain a better understanding of the physical principals operating at cellular level while biophysicist and biomedical engineers will benefit from the solid biology foundation provided by the book.
Section 1: Cell biological aspects of cell movement 1. Cell structure and physiology WANYU ZHAO, WEIDA REN, DICHUN HUANG, YUAN SANG, LINGBO CAO, AND JUNQI HUANG 2. Migrasome in cell movement: new horizon for cell signaling DICHUN HUANG, RUFEI LIN, SHUCHEN LIU, HENGYI ZHONG, ZHANGSHUAI DAI, AND JUNQI HUANG 3. Cellular substructures, actin dynamics, and actin-binding proteins regulating cell migration NATHANIEL L. LARTEY AND MICHAEL SCHNOOR 4. Impact of cell-cell interactions on communication and collectiveness JAZMIN ESPINOSA-RIVERO, CECILIA BANUELOS, AND ABIGAIL BETANZOS 5. Cell migration YUAN-NA LIN AND ANTON WELLSTEIN
Section 2: Mechano-biological aspects of cell movement 6. Fundamental mechanics of cell shape and cell movement YIZENG LI AND SEAN X. SUN 7. Extracellular matrixedependent mechanosensing and mechanotransduction: role in cell migration NATASHA BUWA AND NAGARAJ BALASUBRAMANIAN 8. Cellematrix interactions, force transmission, and mechanosensation CHRISTOPHER WALTER, HANNAH ZMUDA, JOSE A. ALMEIDA, AND AMIT PATHAK
Section 3: Translational aspects of cell movement 9. Cell movement during development WEN-CHAO TANG 10. Cell migration in cardiovascular diseases JENEFA BEGUM, SAMUEL R.C. WEAVER, ASIF J. IQBAL, G. ED RAINGER, AND HELEN M. MCGETTRICK 11. Leukocyte movement during immune responses EDUARDO VADILLO 12. Migrasomes: the "brightest stars in cardiovascular system? ZHANG YAXING, LIU WEI, LIU HAIMEI, ZHOU LEQUAN, YAN FUMAN, GUAN LI, AND XU JINWEN 13. Leukocyte trafficking to the intestinal barrier in health and disease GUSTAVO MONASTERIO, FRANCISCA A. CASTILLO, AND EDUARDO J. VILLABLANCA 14. Cell movement and respiratory diseases ZHI-YING LV, QI MENG, AND LEI-MIAO YIN 15. Cancer cell development, migratory response, and the role of the tumor microenvironment in invasion and metastasis INES M. ANTON, FRANCISCO WANDOSELL, AND MIGUEL VICENTE-MANZANARES
Section 4: Methods and modeling tools for cell movement research 16. Microfluidic tools to study cell migration ROBERTO RODRIGUEZ-MONCAYO, ALAN M. GONZALEZ-SUAREZ, ORESTES LO´ PEZ-ORTEGA, AND JOSE L. GARCIA-CORDERO 17. Using real-time cell analysis to measure cell contraction DONG-DONG ZHOU, JIN LU, AND LEI-MIAO YIN 18. Advanced microscopy techniques for the visualization and analysis of cell behaviors DANIEL MERENICH, KATHLEEN E. VAN MANEN-BRUSH, CHRISTOPHER JANETOPOULOS, AND KENNETH A. MYERS 19. Intravital microscopy IDAIRA M. GUERRERO FONSECA, MICHAEL SCHNOOR, AND EDUARDO VADILLO 20. Mathematical and bioinformatic tools for cell tracking PETER HIRSCH, LEO EPSTEIN, AND LEO GUIGNARD