Biointeractions of Nanomaterials

An examination of the widespread application of nano materials in biology, medicine, and pharmaceuticals and the accompanying safety concerns, Bio-interactions of Nano Materials addresses the issues related to toxicity and safety of nano materials and nano systems. It covers the interactions in biological systems and presents various tools and methods used to evaluate the nano toxicity and nano safety issues. Written by leading scientists, the book focuses on the bio-interaction of nano materials, covering various techniques and tests which have been developed to evaluate the toxicity of materials at the nano level. The book highlights the challenges of bio-interactions of nano materials and possible solutions to those challenges. It addresses the assessment and characterization of nano systems in bio-environments, toxicity and bio-sensing devices for toxicity assessment, carbon nano tubes and pulmonary toxicity, and nano toxicity of solid lipid nanoparticles. It also discusses nano safety concerns and solutions, including the effects of nano particles on different organs and regulatory implications of nano materials. These particles may be used to encapsulate drugs, recognize biological markers, or visualize body tissues among many other possibilities, all enabling their widespread application in biology, medicine, and pharmaceutics. Indeed, these nano materials may have beneficial effects that have not even been imagined. This book gives you an understanding of the safety issues, how to assess for them, and how to mitigate them to move forward in research and development of new applications for nano materials.

Introduction: Biointeractions of Nanomaterials: Challenges and Solutions; Vijaykumar Sutariya, Vrinda Pathak, Ana Groshev, Mahavir Chougule, Sachin Naik, Deepa Patel, Yashwant PathakNanoparticles Exposure in Occupational Environment;Perng-Jy TsaiPhysicochemical Characterization Dependent Toxicity of Nanoparticles; Jigar Shah, Ankur Shah, Hiral Shah, Vijaykumar SutariyaCytotoxicity of Stimuli-responsive Nanomaterials: Predicting Clinical Viability through Robust Biocompatibility Profiles; Daniel Wehrung, Moses O. OyewumiBiosensing Devices for Toxicity Assessment of Nanomaterials; Evangelia Hondroulis, Pratik Shah, Xuena Zhu, Chen-zhong LiCarbon Nanotubes and Pulmonary Toxicity; Malay K Das, Charles PreussNanotoxicity of Polymeric and Solid Lipid Nanoparticles; Dev Prasad, Harsh ChauhanAnalytical Characterization of Nanomaterials in Biological Matrices for Hazard Assessment; Mingsheng Xu, Daisuke Fujita, Huanxing Su, Hongzheng Chen, Nobutaka HanagataNanoparticles and Human Health: A Review of Epidemiological Studies; Vijaykumar Sutariya, Ana Groshev, Vivek Dave, Hardeep Saluja, Deepak Bhatia, Prabodh Sadana , Yashwant PathakToxicogenomic Approach to Understand Toxicity of Nanoparticles; Qiwen Shi, Mahavir B. Chougule, Vijaykumar Sutariya, Deepak BhatiaNanomaterial Based Gene and Drug Delivery: Pulmonary Toxicity Considerations; Mahavir B. Chougule, Rakesh K. Tekade, Peter R. Hoffmann, Deepak Bhatia, Vijaykumar B. Sutariya, Yashwant PathakCardiovascular Toxicity of Nanomaterials; Saijie Zhu, Minghuang HongToxicity of Nanomaterials on Gastrointestinal Tract; Jayvadan Patel, Vibha ChampavatToxicity of Nanomaterials on Liver, Kidney and Spleen; Jayvadan Patel, Anita PatelThe Regulatory Implications of Nanotechnology; Lynn L. Bergeson, Michael F. ColeOcular Toxicity of Nanoparticles; Anjali Hirani, Aditya Grover, YongWoo Lee, Vijaykumar Sutariya, Yashwant PathakGenotoxicity of Nanoparticles; Amaya Azqueta, Leire Arbillaga, Adela López de CerainInteractions of Polysaccharide-Coated Nanoparticles with Proteins; Christine VauthierModels for Risk Assessments of Nanoparticles; Sanjoy Dey, Bhaskar Mazumder, Yaswant PathakImmuno-Toxicity of Carbon Nanoparticles; Paulami Pal, Bhaskar Mazumder, Yaswant Pathak Index