PrefaceContributorsHistory and BackgroundDiscovery of Aspartame - Robert H. MazurSweeteners: An Overall Perspective- George E. InglettMetabolismAbsorption of Peptides, Amino Acids and Their Methylated Derivatives- David M. MatthewsAspartate and Glutamate Metabolism- Lewis D. SteginkPhenylalanine Metabolism- Alfred E. HarperMethanol Metabolism and Toxicity- Thomas R. Tephly and Kenneth E McMartinAspartame Metabolism in Animals- James A. OppermannTissue Distribution of Orally Administered Isotopically Labeled Aspartame in the Rat- Yoshimasa Matsuzawa and Yuichi O’HaraSensory and Dietary AspectsProjected Aspartme Intake: Daily Investigation of Aspartic Acid. Phenylalanine, and Methanol- Roberta Roak-Foltz and Gilbert A. LeveilleComparison of Taste Properties of Apartame with Other Sweeteners- Susan S. SchiffmanAspartame; Implications for the Food Scientist- Barry E. HomlerRole of Sugar and Other Sweeteners in Dental Caries- William H. BowenEfficacy of Low-Calorie Sweeteners in Reducing Food Intake: Studies with Aspartame- Katherine P. Porikos and Theodore B. VanItalliePreclinical StudiesPreclinical Studies of Aspartame in Non-primate Animals- Samuel V. MolinaryChronic Feeding Studies with Aspartame and Its Diketopiperazine- Hiroyuka IshiiArtificial Sweeteners and Bladder Cancer: Assessment of Potential Urinary Bladder Carcinogenicity of Aspartame and Its Diketopiperazine Derivative in Mice- George T. BryanAspartame-Induced Neurotoxicity in Infant Mice-Arnold E. Applebaum, Michael W. Finkelstein, Tahia T. Daabees and Lewis D. SteginkNeuropathology Studies Following Aspartame ingestion by Infant Nonhuman Primates- W. Ann Reynolds, Linda Parsons, and Lewis D. SteginkBehavioral Testing in Rodents Given Food Additives- Richard E. Butcher and Charles V. VorheesDevelopmental Assessment of Infant Macaques Receiving Dietary Aspartame or Phenylalanine- W Ann Reynolds, Anne F. Bauman, Lewis D. Stregink, L. J. Filer Jr, and Sakkubai NaiduEffect of Aspartame on the Learning Test Performance of Young Stumptail Macaques- Stephen J. SuomiAspartame and Brain Tumors: Pathology Issues- Adalbert KoestnerAspartame and Brain Tumors: Statistical Issues- Richard G. Cornell, Robert A. Wolfe, and Paul G. SandersPossible Neurihormonal Effects of Aspartame Investigation- Frank M. SturtevantStudies of Aspartame Metabolism in HumansChronic Ingestion of Aspartame in Humans- Williard J VisekAspartame Metabolism in Humans: Acute Dosing Studies- Lewis D. SteginkAspartame Ingestion During Pregnancy- Roy M. PitkinAspartame Ingestion During Lactation- George L. BakerAspartame Ingestion by Phenylketonuric Heterozygous and Homozygous Individual- Richard Koch and Elizabeth J WenzInteractions of Aspartame and Glutamate Metabolism- Lewis D. SteginkAspartame Use by Persons with Diabetes- David L. HorwitzEffects of Acute Aspartame Ingestion on Large Neutral Amino Acids and Monoamines in Rat Brain- John D. FernstromIndex