Adoptive Cell Transfer

Adoptive Cell Transfer, Volume 370 in the International Review of Cell and Molecular Biology series highlights advances in the field, with this new volume presenting interesting chapters written by an international board of authors who expound on topics such as the Impact of tumor microenvironment on Adoptive Cell Transfer activity, Dendritic Cell Transfer, CAR-T Cell dysfunction and exhaustion, NK Cell-based cancer immunotherapy, Enabling CAR-T cells for solid tumors: rage against the suppressive tumor microenvironment, Improving Adoptive T-Cell therapy with cytokines administration, and What will (and should) be improved in Immunotherapy with CAR?

• Publishes only invited review articles on selected topics
• Authored by established and active cell and molecular biologists and drawn from international sources
• Offers a wide range of perspectives on specific subjects

Clément Thomas is holding a group leader position at the Department of Oncology of the Luxembourg Institute of Health (LIH; Luxembourg City, Luxembourg). He received his PhD in Molecular and Cellular Biology in 2003 from Strasbourg University (France) in 2003. Since that moment, he has been interested in cell plasticity with a particular focus on actin cytoskeleton remodeling mechanisms. After more than ten years working with plant models, he joined the department of Oncology of LIH and established a group focused on the functions of the actin cytoskeleton in two central and complementary processes underlying cancer progression: invasion and immune evasion. Clément Thomas and his colleagues characterized a family of small, evolutionary-conserved, LIM domain-containing proteins (cysteine and glycine-rich proteins) that crosslink actin filaments into stable actin bundles and established the role of these proteins in promoting the formation and activity of invadopodia in breast cancer cells. Lately, Clément Thomas' group has initiated a pioneering study aimed at elucidating the role of the cancer cell's actin cytoskeleton during immune evasion.
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome "La Sapienza . Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology.

Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals:
OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.