The Bipolar Brain

In this book, experts in neuroimaging and genetics discuss recent discoveries in bipolar disorder, leading to an integrated neurophysiologic model of this condition. This model provides a substrate for future investigations to, hopefully, lead to better understanding of this illness in order to develop improved therapies for affected individuals.

Section I: How neuroimaging informs models of bipolar disorder.; Chapter 1. Brain imaging techniques and their application to bipolar disorder.; by Caleb M. Adler and Michael Cerullo; Chapter 2. Structural brain abnormalities in bipolar disorder.; by Koji Matsuo, Marsal Sanches, Paolo Brambilla, and Jair C. Soares; Chapter 3. Functional brain imaging in bipolar disorder; by Lori L. Altshuler and Jennifer Townsend; Chapter 4. Neurochemical and metabolic imaging in bipolar disorder; by Jieun E Kim, In Kyoon Lyoo, and Perry F Renshaw,; Chapter 5. Neuroimaging studies of bipolar disorder in youth.; by Manpreet K. Singh, Melissa P. DelBello, and Kiki D. Chang; Chapter 6. Neuroimaging difference between bipolar and unipolar depression.; by Amelia Versace, Jorge R.C. Almeida, and Mary L. Phillips; Chapter 7. Neuroimaging in bipolar disorder and schizophrenia.; by Heather Whalley, Jessika Sussman, and Andrew M. McIntosh; Section II: How genetic research informs models of bipolar disorder.; Chapter 8. Genetic techniques and their application to bipolar disorder.; by Aaron C. Vederman and Melvin G. McInnis; Chapter 9. General genetic findings in bipolar disorder.; by John I. Nurnberger, Jr.; Chapter 10. Genetics of bipolar disorder and schizophrenia.; by Michael E. Talkowski, Kodavali V Chowdari, Hader Mansour, K M Prasad, Joel Wood, and Vishwajit L Nimgaonkar; Chapter 11. Mitochondrial genetics and bipolar disorder.; by Hayley B. Clay, Satoshi Fuke, Tadafumi Kato, and Christine Konradi; Section III: Integration and future directions.; Chapter 12. Personalized medicine - can genetics and imaging inform treatment; by Roy H. Perlis and Hilary P. Blumberg; Chapter 13. Integration and consolidation - a neurophysiological model of bipolar disorder.; by Stephen M. Strakowski