Marine Biomaterials Characterization, Isolation and Applications

Oceans are an abundant source of diverse biomaterials with potential for an array of uses. Marine Biomaterials: Characterization, Isolation and Applications brings together the wide range of research in this important area, including the latest developments and applications, from preliminary research to clinical trials. The book is divided into four parts, with chapters written by experts from around the world. Biomaterials described come from a variety of marine sources, such as fish, algae, microorganisms, crustaceans, and mollusks. Part I covers the isolation and characterization of marine biomaterials—bioceramics, biopolymers, fatty acids, toxins and pigments, nanoparticles, and adhesive materials. It also describes problems that may be encountered in the process as well as possible solutions. Part II looks at biological activities of marine biomaterials, including polysaccharides, biotoxins, and peptides. Chapters examine health benefits of the biomaterials, such as antiviral activity, antidiabetic properties, anticoagulant and anti-allergic effects, and more. Part III discusses biomedical applications of marine biomaterials, including nanocomposites, and describes applications of various materials in tissue engineering and drug delivery. Part IV explores commercialization of marine-derived biomaterials—marine polysaccharides and marine enzymes—and examines industry perspectives and applications. This book covers the key aspects of available marine biomaterials for biological and biomedical applications, and presents techniques that can be used for future isolation of novel materials from marine sources.

Part I: Isolation and Characterization of Marine Biomaterials Introduction to Marine BiomaterialsSe-Kwon Kim and Jayachandran VenkatesanHydroxyapatite from Marine Fish Bone: Isolation and Characterization TechniquesJayachandran Venkatesan and Se-Kwon KimHydroxyapatite and Calcium Phosphates from Marine Sources: Extraction and CharacterizationClara Piccirillo, Manuela M. Pintado, and Paula M.L. CastroIsolation and Characterization of Chitin and Chitosan as Potential BiomaterialsNitar Nwe, Tetsuya Furuike, and Hiroshi TamuraStructure Elucidation and Biological Effects of Carrageenans from Red AlgaeWei Zhang, Ming Liu, and Poul Erik HansenA Study of Marine-Derived Fatty Acids and Their Therapeutic ImportanceParimal C. SenMarine Toxins for Natural Products Drug DiscoveryMuthuvel Arumugam, Thangavel Balasubramanian, and Se-Kwon KimConotoxins: A Source of Biomaterial for Pharmacology and NeuroscienceNgo Dang NghiaPigmented Marine Heterotrophic Bacteria: Occurrence, Diversity, and Characterization of PigmentationMarit H. Stafsnes and Per BruheimAntitumor Pigments from Marine BacteriaAzamjon B. Soliev and Keiichi EnomotoStructural Characteristics of Bioactive Marine Natural ProductsSnezana Agatonovic-Kustrin, David Morton, and Christine KettleEnvironmental and Human Impact on Marine Microorganism–Synthesized NanoparticlesL. Karthik, Gaurav Kumar, and K.V. Bhaskara RaoBiosynthesis and Characterization of Different Nanoparticles and Its Larvicidal Activity against Human Disease VectorsArivarasan Vishnu Kirthi, Chidambaram Jayaseelan, and Abdul Abdul RahumanMussel-Derived Adhesive BiomaterialsDong Soo Hwang, Yoo Seong Choi, and Hyung Joon ChaPart II Biological Activities of Marine BiomaterialsBiological Applications of Marine BiomaterialsA. Malshani Samaraweera and Janak K. VidanarachchiHealth Benefits of Sulfated Polysaccharides from Marine AlgaeSe-Kwon Kim, Dai-Hung Ngo, Thanh-Sang Vo, and Dai-Nghiep NgoBiological Activities and Potential Applications of Marine BiotoxinsAlberto Otero, María José Chapela, Jorge Lago, Juan M. Vieites, and Ana G. CabadoCompounds from Marine Organisms with Antiviral ActivitySe-Kwon Kim, Fatih Karadeniz, and Mustafa Zafer KaragozluBiological Activities of Marine-Derived Bioactive PeptidesChen Zhang, Yuanfeng Ruan, and Se-Kwon KimHealth Beneficial Effects of Docosahexaenoic Acid: A Marine TreasureNa-Young Song and Young-Joon SurhTreatment of Obesity and Diabetes with Marine-Derived BiomaterialsSe-Kwon Kim, Fatih Karadeniz, and Mustafa Zafer KaragozluPotential Anticoagulant Effect of Seaweed-Derived BiomaterialsSe-Kwon Kim and Quang Van TaMicrobial Biomaterials and Their ApplicationsSe-Kwon Kim, Ira Bhatnagar, and Ramjee PallelaMarine Biomaterials for Antiallergic TherapeuticsSe-Kwon Kim, Thanh-Sang Vo, and Dai-Hung NgoPart III Biomedical Applications of Marine BiomaterialsBiomedical Potential of Unchlorinated Briarane Diterpenes from Gorgonians and Sea PensBruce F. Bowden and Ioana M. VasilescuApplication of Marine Collagen-Based Scaffolds in Bone Tissue EngineeringRamjee Pallela, Jayachandran Venkatesan, Ira Bhatnagar, Yoon-Bo Shim, and Se-Kwon KimBiocomposites Containing Chitosan for Bone Tissue EngineeringSekaran Saravanan, Mohita Trivedi, Ambigapathi Moorthi, and Nagarajan SelvamuruganMarine Plants and Algae as Promising 3D Scaffolds for Tissue EngineeringM. López-Álvarez, J. Serra, J.M. Sánchez, A. de Carlos, and P. GonzálezApplication of Marine Biomaterials in Orthopedic and Soft Tissue Surgical ChallengesSamit Kumar Nandi, Uttam Datta, and Subhasish BiswasMarine Materials in Drug Delivery and Tissue Engineering: From Natural Role Models to Bone Regeneration and Repair and Slow Delivery of Therapeutic Drugs, Proteins, and GenesBesim Ben-Nissan and David W. GreenPolysaccharides from Seaweeds: Modification and Potential Application in Drug DeliveryHéctor J. Prado, María C. Matulewicz, Pablo R. Bonelli, and Ana L. CukiermanMarine Biomaterials: Role in Drug Delivery and Tissue Engineering toward Biomedical ApplicationsDevarai Santhosh Kumar and Kota SobhaApplication of Marine Biomaterials for Gene DeliveryYou-Kyoung Kim, Hu-Lin Jiang, Bijay Singh, Yun-Jaie Choi, Myung-Haing Cho, Toshihiro Akaike, and Chong-Su ChoAdvantages of Chitin-Based Nanobiomaterials in NanomedicineS. Sowmya, Shantikumar V. Nair, and R. JayakumarChitin Nanofibrils for Biomimetic Products: Nanoparticles and Nanocomposite Chitosan Films in Health CareP. Morganti, G. Tishchenko, M. Palombo, I. Kelnar, L. Brozova, M. Spirkova, E. Pavlova, L. Kobera, and F. CarezziRole of Nanocomposites and Nanostructured Biomaterials in Biomedical and NanobiotechnologyAbdul Bakrudeen Ali Ahmed, R. Arun Kumar, and Rosna Mat TahaPart IV: Industrial Applications of Marine-Derived BiomaterialsIndustry Perspectives of Marine-Derived Proteins as BiomaterialsSe-Kwon Kim, Dai-Hung Ngo, Thanh-Sang Vo, and BoMi RyuMarine Polysaccharide (Chitosan) and Its Derivatives as Water PurifierY. Dominic Ravichandran and R. RajeshIndustrial Applications of Marine PolysaccharidesS.N. Joshi, A.N. Bedekar, and P.N. SudhaApplication of Enzymes from Marine MicroorganismsXiujuan Shi, E. Song, and Chen ZhangIndex

Professor Se-Kwon Kim, Ph.D., is a senior professor in the Department of Chemistry and is the director of the Marine Bioprocess Research Center (MBPRC) at Pukyong National University in the Republic of Korea. His major research interests include investigation and development of bioactive substances derived from marine organisms and their application in Oriental medicine, nutraceuticals, and cosmeceuticals via marine bioprocessing and mass-production technologies. He is a board member of the International Society of Marine Biotechnology and the International Society for Nutraceuticals and Functional Foods. To date, he has authored more than 500 research papers, holds 110 patents, and has written or edited more than 40 books.